The AUDIT-C screening tool (≥3 points for women, ≥4 for men) combined with the Fibrosis-4 blood test represents a practical two-step approach for identifying alcohol-associated liver disease before symptoms appear. Sequential testing using both blood markers and imaging significantly improves diagnostic accuracy compared to blood tests alone, potentially catching liver damage years earlier than current practice allows. This systematic screening framework addresses a critical gap in preventive medicine, as alcohol-associated liver disease often progresses silently until advanced stages when treatment options become limited. The multidisciplinary model integrating mental health services directly into medical settings acknowledges that alcohol use disorder and liver disease require simultaneous treatment rather than sequential referrals that often fail. Early intervention protocols like screening, brief intervention, and referral to treatment have demonstrated effectiveness in non-dependent drinkers, suggesting that population-wide implementation could substantially reduce the trajectory toward severe liver disease. The emphasis on substance use navigators and specialized ALD clinics reflects growing recognition that traditional episodic care models inadequately serve patients with complex addiction-related medical conditions requiring sustained engagement and coordinated treatment approaches.