Brain recordings from 11 epilepsy patients living at home revealed that seizures trigger specific alterations in subsequent sleep architecture. Post-seizure nights showed reduced REM sleep duration alongside increased slow-wave sleep duration and enhanced slow-wave spectral power, with the most pronounced changes occurring within the same brain regions that generate seizures. These modifications mirror patterns observed during normal memory consolidation, where slow-wave sleep strengthens neural connections. The parallel suggests seizures may hijack the brain's natural memory consolidation machinery to reinforce pathological neural circuits—a phenomenon termed seizure-related consolidation. This represents a paradigm shift in understanding epilepsy progression, moving beyond viewing seizures as isolated events to recognizing them as potentially self-reinforcing through sleep-mediated synaptic strengthening. The finding could explain why epilepsy tends to worsen over time and why seizure clusters often occur. For the 50 million people worldwide with epilepsy, this research opens new therapeutic avenues. Targeted disruption of post-seizure sleep patterns might prevent the consolidation of epileptic networks, offering a novel approach to epilepsy management that addresses root mechanisms rather than just suppressing seizure activity.