Post-cesarean surgical site infections affect 3-15% of the 21% of global births delivered by C-section, creating a substantial burden despite sophisticated antiseptic protocols and prophylactic antibiotics. These infections span from superficial incisional complications to life-threatening necrotizing soft tissue infections, with polymicrobial pathogens varying by infection depth and location. This persistent infection rate represents a significant healthcare challenge given cesarean delivery's status as the world's most common major surgery. The findings underscore how even well-established surgical procedures carry infectious complications that modern medicine hasn't fully conquered. Risk factors including prolonged membrane rupture, elevated BMI, and extended operative times suggest patient-specific vulnerabilities that standard protocols may inadequately address. The review's emphasis on necrotizing infections highlights how some cases progress to medical emergencies requiring immediate intervention. For expectant mothers, this data reinforces the importance of discussing infection prevention strategies with surgical teams, particularly for those with identified risk factors. The gap between current prevention methods and actual outcomes suggests room for innovation in perioperative care protocols, potentially through personalized risk assessment or enhanced antimicrobial strategies tailored to individual patient profiles.