The Buck Institute has established a dedicated Reproductive Biology Hub to investigate how female reproductive biology intersects with aging processes. This specialized facility addresses a significant research gap, as most aging studies have historically focused on male subjects or ignored sex-specific factors entirely. The hub represents a strategic pivot toward understanding how hormonal transitions, particularly menopause, influence healthspan and longevity outcomes in women. This initiative could prove transformative for aging research, given that women comprise roughly 60% of the population over 65 and experience unique age-related health challenges tied to reproductive biology. The facility's focus on reproductive aging may unlock insights into why women have longer lifespans but often experience more years of disability compared to men. While the specific research protocols and initial findings remain to be seen, this institutional commitment signals recognition that female biology requires dedicated study rather than extrapolation from male-dominated research. The hub's establishment may catalyze broader industry attention to sex differences in aging, potentially leading to more personalized interventions for women's healthspan optimization.