A novel catheter-integrated biosensor achieves real-time detection of bacterial concentrations indicative of urinary tract infections, potentially identifying infections 12-24 hours before conventional urine cultures yield results. The device wirelessly transmits data to smartphones, enabling continuous monitoring without additional patient procedures. This technology addresses a critical gap in hospital-acquired infection prevention, where catheter-associated UTIs represent the largest subset of healthcare-associated infections. Traditional culture methods require 24-48 hours for bacterial growth confirmation, during which infections can progress to more serious complications like sepsis or kidney involvement. Early intervention is crucial since UTI treatment success rates exceed 95% when antibiotics are initiated within the first 24 hours of symptom onset. The sensor's ability to differentiate between pathogenic bacteria and normal urinary microbiota could reduce unnecessary antibiotic prescriptions while ensuring appropriate treatment timing. For immunocompromised patients and elderly individuals who often present with atypical UTI symptoms, continuous monitoring could prevent diagnostic delays that frequently lead to severe complications. If validated in larger clinical trials, this technology could transform infection control protocols in intensive care units and long-term care facilities.