A comprehensive care protocol combining chlorhexidine antiseptic, prophylactic antibiotics, and enhanced hygiene practices reduced maternal infections during delivery by 35% across multiple hospital sites. The intervention targeted the leading preventable cause of maternal mortality worldwide, demonstrating measurable impact through systematic implementation of evidence-based practices. This finding represents a significant advancement in maternal safety protocols, particularly relevant as healthcare systems grapple with rising infection rates and antibiotic resistance. The bundled approach mirrors successful infection control strategies used in surgical settings, suggesting that standardized protocols can translate complex clinical guidelines into actionable bedside practices. For expectant mothers, this research validates the importance of delivery facility infection control standards when choosing birthing locations. The study's strength lies in its real-world implementation across diverse hospital environments, though the specific patient populations and baseline infection rates require scrutiny to assess generalizability. While individual components of the bundle have shown promise in smaller studies, this larger-scale validation could accelerate adoption of comprehensive maternal safety protocols. The intervention's success hinges on consistent staff training and supply chain reliability, factors that may limit implementation in resource-constrained settings where maternal infections remain most prevalent.