Analysis of 3,417 young adults in the CARDIA cohort reveals that adverse childhood family environments create a distinctive cardiovascular signature during exercise. Participants with higher childhood adversity scores showed lower initial blood pressure and heart rate at rest, but demonstrated steeper increases in systolic pressure, heart rate, and pulse pressure as exercise intensity increased. The effect size was modest but consistent across multiple cardiovascular measures. This finding suggests that early life stress may program the cardiovascular system to respond more reactively to physical demands, even decades later. The exaggerated exercise pressor response could represent a mechanistic pathway linking childhood trauma to elevated cardiovascular disease risk in adulthood, complementing existing research on chronic inflammation and metabolic dysfunction as mediators. However, the clinical significance of these relatively small effect sizes remains unclear, and the observational design cannot establish causation. As this is a preprint awaiting peer review, these cardiovascular programming effects require validation through independent replication and longer-term outcome studies to determine whether altered exercise responses translate to meaningful health consequences.