New epigenetic clock research reveals that early-life adversity triggers faster cellular aging in women compared to men, with DNA methylation patterns showing distinct sex-specific responses to trauma exposure. The study measured biological age acceleration using multiple epigenetic markers, finding that women who experienced childhood adversity showed significantly greater acceleration of cellular aging processes than their male counterparts with similar trauma histories. This differential aging response appears linked to sex-specific stress hormone pathways and inflammatory cascades that leave lasting epigenetic signatures. The findings help explain why women often show higher rates of age-related diseases following early trauma, despite generally living longer than men. This research bridges two important gaps in aging science: the mechanistic connection between psychological stress and biological aging, and the underexplored role of biological sex in determining resilience to adversity. For health-conscious adults, particularly women with adverse childhood experiences, this suggests that targeted interventions addressing stress-related aging may be especially beneficial. The work also indicates that one-size-fits-all approaches to healthy aging may miss critical sex-specific vulnerabilities, pointing toward more personalized longevity strategies based on individual trauma history and biological sex.