Longevity
Uremic Toxins Linked to Kidney-Brain Axis Cognitive Decline Through Multiple Mechanisms
Cognitive decline has long been attributed to aging, genetics, and cardiovascular risk — but mounting evidence…
Studies
Modified RNA Reprogramming Triggers Exosomal miRNA Signals That Shield Heart Cells
Heart muscle cells that die after injury rarely come back — and that irreversibility underpins much of the global…
Studies
Postmortem TB Diagnoses in England Reveal Fatal Gaps in Older Male Patients
Tuberculosis remains a disease of profound diagnostic inequity, and the most extreme form of that inequity is when the…
Studies
Deep Learning Flags Young-Onset Diabetes Risk 118-Fold Above Population Baseline
Type 2 diabetes in adults under 40 is not a minor variant of the classic disease — it carries faster complication…
Studies
Lipid Kinase PIKfyve Controls Retinal Cell Survival via Lysosomal Clearance
Age-related and inherited retinal degenerations share a common bottleneck: the cellular machinery responsible for…
Studies
Pre-Monsoon Salinity Surge Linked to Chattogram Cholera Spike
Cholera's relationship with climate is more intimate than most people realize — and a 2023 outbreak in coastal…
Nutrition
First 1000 Days Sugar Restriction Linked to 27–46% Lower Dementia Risk
The foods a child eats in their first two years of life may shape the trajectory of their brain decades later — a…
Studies
GBM Spatial Drug Sensitivity Maps Reveal Core-Margin Therapeutic Divergence
Glioblastoma's near-universal lethality has long been attributed not just to its aggressiveness but to the fact that…
Studies
Medicare Drug Cost Cap Linked to Measurable Drop in Skipped Medications
For millions of older Americans managing chronic conditions, the decision to skip or ration a prescription due to cost…
Nutrition
GLP-1 Paired Digital Nutrition Tool Sustains Weight Loss in 78-Person Pilot
A web-based Personalized Nutrition Advisor (PNA) dashboard tested alongside GLP-1 receptor agonist (GLP-1 RA) therapy…
Longevity
PGC-1α/FNDC5/BDNF Pathway Links Sarcopenia to Accelerating Cognitive Decline in Aging
Synthesizing 68 primary studies and reviews (PubMed/Scopus/Web of Science, 2000–2026), this narrative review maps the…
Longevity
Marmosets and Macaques May Unlock Human Gut-Aging-Inflammaging Mechanisms
Age-associated gut dysbiosis drives inflammaging — chronic low-grade inflammation — through gut barrier dysfunction…
Longevity
ALY688 Peptide Cuts Infarct Size Via Gut-Heart Immune Axis in Rats
ALY688, a synthetic adiponectin receptor agonist peptide, delivered during ischemia or at reperfusion and daily for 28…
Wellbeing
Danish Veterans Study Validates Moral Injury Scale Beyond PTSD Measures
For clinicians treating combat veterans, distinguishing moral injury from post-traumatic stress disorder is not merely…
Studies
Mouse Model of Dravet Syndrome Shows Long-Lasting Astrocyte Network Remodeling Without Structural Brain Loss
When a severe childhood epilepsy leaves no visible scar on brain tissue, the damage may still be written in the cells…
Studies
Large Language Model Surpasses Physicians on Clinical Reasoning Across Five Experiments
When a machine consistently outperforms trained physicians on the very tests designed to certify medical expertise…
Studies
Phase III Trial: Silver Diamine Fluoride Arrests Cavities in 830 Young Children
Tooth decay remains the most common chronic disease in childhood, yet effective, accessible treatments beyond drilling…
Studies
Synchronizing FXR Agonist Timing With Bile Acid Cycles May Boost Liver Therapy
Most pharmacological interventions treat receptor activation as a static on/off switch, but mounting evidence suggests…
Studies
FGFR2 Receptor Drives EBV-Linked Lymphoma, Suggesting Targeted Therapy Pathway
Virus-driven cancers account for roughly 15–20% of all human malignancies worldwide, yet targeted treatment options…
Studies
Glial Cells in Distinct Brain Regions Independently Gate Seizure Triggers
Epilepsy research has long focused on neurons as the primary drivers of seizure activity, but mounting evidence…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.