PREPRINTWellbeing
Single-Parent Neighborhoods Show 2.65x Higher Mortality After Heart Valve Procedures
A retrospective analysis of 727 consecutive patients undergoing transcatheter aortic valve replacement (TAVR) found tha…
Fitness
WHO Data Reveals Physical Activity Benefits Extend Beyond Heart Disease
Global health surveillance is finally capturing the full spectrum of physical activity's protective effects, moving bey…
Longevity
Daily Multivitamins Slow Biological Aging by 1.8 Years in Major Trial
The possibility of slowing biological aging through simple daily supplementation has moved from speculation to measurab…
Supplements
Multivitamin Supplementation Reduces Biological Age Markers in Epigenetic Analysis
The relationship between nutritional supplementation and cellular aging has entered unprecedented territory with eviden…
Supplements
Synthetic Compound Activates Key Antioxidant Enzyme Through Molecular Engineering
The development of targeted antioxidant therapies represents a frontier in combating cellular aging and oxidative stres…
Supplements
Berberine Blocks Key Inflammatory Pathways in Mouse Model of Ischemia-Reperfusion Injury
Tissue damage from blocked blood flow followed by restoration—common during heart attacks, strokes, and surgeries—may b…
Studies
New Vaccine Technologies Target Rising Mosquito-Borne Disease Threats
Climate change and global urbanization are creating perfect conditions for mosquito-transmitted diseases to flourish in…
Studies
Fecal Transplants Boost Cancer Immunotherapy Response in Three Trials
Cancer patients may soon have access to a breakthrough combination therapy that harnesses gut bacteria to amplify their…
Wellbeing
Adenosine Surge in Brain's Prefrontal Cortex Drives Rapid Depression Relief
The mystery of why ketamine and electroconvulsive therapy work so rapidly for severe depression may finally be solved,…
Wellbeing
Ultrafine Candle Nanoparticles Persist at Dangerous Indoor Concentrations
Indoor air quality concerns have largely overlooked the smallest airborne threats—ultrafine nanoparticles measuring jus…
Longevity
Genetic Analysis Reveals Shared Brain Aging Pathway Across Global Populations
Premature brain aging predicts cognitive decline, dementia risk, and mortality across populations, but measuring it acc…
Longevity
Parkinson's Disease and Frailty Share Bidirectional Relationship Through Aging Pathways
The intersection of neurodegeneration and physical decline reveals a complex feedback loop that could transform how cli…
Wellbeing
Vascular Dementia Treatments Show Modest Gains While Prevention Remains Key
Twenty percent of dementia cases stem directly from vascular origins, yet therapeutic progress has lagged dramatically…
Studies
Combined Saliva Bacteria and Blood Markers Predict Childhood Asthma Attacks
Preventing severe asthma attacks in children requires identifying who faces the highest risk before emergency situation…
Nutrition
High-Fiber Pregnancy Diets Linked to Higher Levels of Beneficial Microbes, Lower Inflammatory Species
The composition of gut bacteria during pregnancy may hold keys to preventing gestational diabetes, hypertension, and ot…
Studies
Oral Pathobiont Fusobacterium Nucleatum Drives Cancer Through Multiple Mechanisms
The emerging recognition that certain microbes function as cancer drivers represents a paradigm shift in oncology, movi…
Studies
Brain Lesion Study Maps Neural Networks Essential for Mental Imagery
The mystery of why some people cannot conjure mental images may finally have a clear neurological explanation, with imp…
Wellbeing
Sleep Duration and Chemotherapy Associated With 39% Cognitive Impairment Rate in Pediatric Cancer
Nearly four in ten children battling cancer experience measurable cognitive decline, a finding that challenges assumpti…
Studies
Dual PI3K/mTOR Inhibitor Overcomes Resistance to CDK4/6 Inhibitors and Endocrine Therapy in ER+ Breast Cancer
The emergence of treatment-resistant breast cancer represents one of oncology's most formidable challenges, particularl…
Studies
Semaglutide Associated with Fecal Impaction in Patient with Long-Term Ileostomy
A 56-year-old man with an ileostomy developed severe fecal impaction requiring hospitalization after restarting semaglu…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.