Studies
GI Cancers Before 50 Rising Globally: Microbiome and Metabolism Implicated
A troubling epidemiological inversion is underway in gastrointestinal oncology: cancers of the colon, rectum, stomach…
Studies
Global TB Burden Mapped Across 204 Nations: MDR-TB Threatens 2035 Targets
Tuberculosis remains one of the most consequential infectious disease challenges of the modern era, and understanding…
Studies
65% Exacerbation-Free at One Year After Stopping Severe Asthma Biologics
For the roughly one-third of severe asthma patients on biologics who eventually stop treatment — whether by choice…
Studies
VR and AR in Shoulder Surgery: Promising Tools, Still Limited Evidence
As digital tools reshape orthopedic surgery, understanding which technologies are ready for the operating room versus…
Studies
BTK Inhibitors Cross Blood-Brain Barrier, Targeting Progressive MS Pathology
For the roughly 15% of multiple sclerosis patients who never experience relapses and the larger proportion whose…
Studies
First Phase 3 Trial Shows Oral AD109 Reduces Sleep Apnea Severity by 44%
For the roughly 30–50% of sleep apnea patients who cannot or will not tolerate CPAP machines, the absence of a proven…
Wellbeing
Estrogen Decline Maps to Six Cognitive Domains in Menopausal Women
For roughly half the global population, the menopausal transition represents an underappreciated neurological…
Nutrition
Polyphenol Mix Raises LDL Numbers Yet Cuts Oxidized LDL in Postmenopausal Women
Standard lipid panels may be telling an incomplete story for postmenopausal women taking polyphenol supplements. When…
Longevity
Midlife GDF15 Protein Predicts Dementia Risk 25 Years Later via Neuroimmune Pathways
Most dementia risk scores focus on lifestyle factors and genetics measured close to diagnosis — but a growing body of…
Studies
CDT Thrombolysis Trial Redefines Clot Treatment for High-Intermediate PE Risk
Pulmonary embolism sits at a dangerous crossroads where undertreatment risks death and overtreatment risks…
Studies
Tirzepatide and CagriSema Lead 19-Drug Obesity Meta-Analysis Covering 99,000 Patients
The landscape of obesity pharmacotherapy has shifted so rapidly in the last five years that clinicians and patients…
Studies
Phase 3 Trial: Atezolizumab Fails EFS in Early TNBC, But Tumor Subtype Signal Emerges
Triple-negative breast cancer remains one of oncology's most difficult targets precisely because it lacks the…
Studies
Global TB Burden Mapped Across 204 Nations: MDR-TB and HIV Co-infection Trends 1990–2023
Tuberculosis remains one of the most consequential infectious disease challenges of our era, and at a moment when…
Nutrition
Fluconazole Reshapes IBD Gut Fungal Balance Where Nystatin Falls Short
For the millions living with inflammatory bowel disease, the gut microbiome's bacterial inhabitants have long…
Longevity
NRF2 Pathway in Oligodendrocytes Linked to Variable Cognitive Aging Rates
Most interventions targeting age-related cognitive decline have focused on neurons, amyloid plaques, or tau tangles…
Studies
Blood Protein ISM2 Flags Preeclampsia Risk in First Trimester
Identifying dangerous pregnancy complications before symptoms emerge has long been one of obstetric medicine's most…
Studies
Global TB Burden Mapped Across 204 Nations: MDR-TB Progress Lags Dangerously
With global health funding under unprecedented pressure and WHO's 2035 End TB targets still a distant aspiration for…
Studies
Benzylpenicillin Matches Anti-Staphylococcal Penicillins in PSSA Bloodstream Infection
For decades, clinicians have defaulted to broader anti-staphylococcal penicillins even when bloodstream infections are…
PREPRINTLongevity
Post-TAVI Butyrate Decline Correlated with IL-18 Elevation via Gut-Immune Axis in Small Preprint Study
In 40 patients undergoing transcatheter aortic valve implantation (TAVI), circulating short-chain fatty acid (SCFA)…
PREPRINTStudies
730-Case SEER Registry Reveals Two Distinct Cardiac Tumor Types With Divergent Survival Profiles
Among 730 primary malignant cardiac tumor (PMCT) cases from the SEER-18 registry (2000–2021), two biologically…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.