Longevity
Blood Stem Cell Aging Mechanisms Reveal Promising Rejuvenation Pathways
The blood system is quietly central to how we age. Hematopoietic stem cells (HSCs) orchestrate lifelong immune…
Studies
CFTR Modulator Pharmacokinetics Shift Significantly in Pediatric Liver Disease
For children with cystic fibrosis who also develop advanced liver disease, treatment options narrow considerably — and…
Studies
66 Radionuclide-Drug Conjugates Mapped for Lung Cancer Precision Targeting
Lung cancer kills more people annually than any other malignancy, and the persistence of drug resistance alongside…
Studies
Rwanda's 2024 Marburg Outbreak Yields Six Containment Lessons for Global Preparedness
When a hemorrhagic fever with no approved treatments and case fatality rates historically exceeding 80% strikes an…
Studies
Largest Proteogenomic Map Links 24,000 Genetic Variants to Disease Drug Targets
When the same genetic variants that regulate circulating proteins also associate with disease risk, researchers gain…
PREPRINTStudies
iPad-Based Remote Neurological Exam Achieves 96% Success Across 25 Diabetes-Alzheimer's Sites
A standardized video-based asynchronous neurological examination (VANE) deployed across 25 clinical sites in the…
PREPRINTStudies
362 Physicians Reveal Dangerous Gaps in Hyperkalemia Care Across 7 Nations
A cross-sectional survey of 362 physicians across seven Central American countries and the Dominican Republic reveals…
PREPRINTStudies
Vaccine-Targeted Pneumococcal Strain Persists via 3 Co-Circulating Lineages, Not Local Clones
Despite high pneumococcal conjugate vaccine (PCV) coverage, serotype 19F — a strain the vaccine is specifically…
PREPRINTStudies
US Air Pollution Policies Prevented 7% of NYC Respiratory ER Visits Over 14 Years
Counterfactual modeling across New York City, Los Angeles, and Atlanta from 2005 to 2019 quantifies what air quality…
PREPRINTStudies
5-Year Azithromycin Mass Dosing Fails to Cut Enteric Fever Seroincidence in Niger Children
A secondary analysis of the MORDOR cluster-randomized trial in 30 rural Niger communities found that biannual…
Studies
Semaglutide Captures 42.7% of Croatia's Antidiabetic Spend by 2024
GLP-1 receptor agonist utilization in Croatia climbed from near zero at market entry to 15.99 defined daily doses per…
Fitness
Resistance Training Boosts Muscle Quality SMD 0.61 in Older Adults
Across 41 randomized controlled trials encompassing 3,141 adults aged 60 and older, resistance exercise emerged as the…
Studies
Poor Sleep Associated with Depleted Levels of Gut Bacterium Eubacterium CAG:251 in 869 Older Adults
Among 869 older adults (mean age 70.7) in the Baltimore Longitudinal Study of Aging, both subjective insomnia symptoms…
Longevity
JAK Inhibitor Ruxolitinib Blocks Radiation-Induced Bone Loss via SASP Suppression
Ruxolitinib, a clinically approved JAK1/2 inhibitor, administered early and intermittently during radiotherapy…
Studies
Screening Ultrasound After Negative Tomosynthesis: 98.5% False-Positive Rate Quantified
For women with dense breasts, the decision to add ultrasound screening on top of a negative mammogram carries real…
Fitness
NEJM Perspective: 'Last Man Running' Offers Personal Reflection on Aging and Running
For adults tracking the intersection of physical activity and healthy aging, a perspective piece in the New England…
Wellbeing
Secure Attachment Early in Life May Buffer Against Persistent PTSD
The relationship between early childhood experience and long-term psychological resilience is one of the most…
PREPRINTStudies
60% Seroprevalence: Highland Communities Face 5× Greater Scrub Typhus Exposure Than Thai Lowlanders
A population-based serosurvey of 1,194 adults across 74 villages in Chiang Rai province, Thailand (2023) found IgG…
PREPRINTWellbeing
Austria's Oldest-Old Men Face 33.2/100k Suicide Rate, Widowhood a Key Factor
Analyzing 2,442,939 Austrians aged 65+ across 2014–2023, this nationwide retrospective cohort study identified 4,724…
PREPRINTStudies
Texas Identified as Primary Entry Point for Cyclospora Parasite in 25-Year Genomic Map
Applying phylogenetic network analysis via the StrainHub framework to mitochondrial sequence data from 1997–2022…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.