Studies
Pain Perception and Nerve Sensitization Can Operate Independently in Humans
One of pain medicine's most persistent assumptions is that how much something hurts maps directly onto how activated…
Studies
Long-Read Sequencing Reveals Previously Undetectable Mitotic DNA Crossover Events
Understanding how errors accumulate in dividing cells matters enormously for cancer biology, aging, and the stability…
Studies
RNA-Binding Protein Inhibition Dismantles HPV Oncoproteins, Restoring Tumor Suppression
Even with prophylactic HPV vaccines protecting against new infections, millions of people worldwide already harbor…
Wellbeing
Chloride-Sensing Kinase WNK1 Phosphorylates Gephyrin to Control GABA Receptor Density
Anxiety disorders affect roughly one in three adults over a lifetime, yet the molecular machinery governing how the…
Studies
NEDD4L Ubiquitin Enzyme Drives CB1 Receptor Tolerance to Cannabinoids
For the millions of patients using cannabis-derived medicines for pain, epilepsy, or anxiety, the gradual erosion of…
Studies
Mammalian Genomes Harbour RNA Structures That Sense Sodium and Lithium
The assumption that riboswitch-like RNA sensors belong exclusively to bacteria may need serious revision. If mammalian…
Studies
Gut Fungus Mucor racemosus Reprograms Metabolism to Shield Against Radiation Damage
Most people think of gut health in terms of bacteria, but a growing body of evidence suggests the fungal residents of…
Studies
Primate AD Model Links Neuronal Network Disorganization to Early Cognitive Decline
Understanding exactly when and how Alzheimer's disease begins to erode cognition — before plaques accumulate visibly…
Studies
Single-Molecule Imaging Reveals MHC-I Complexes Are Monomeric, Not Clustered
How immune cells physically display threat signals to killer T cells has been debated for decades, and a long-standing…
Studies
Forebrain Ankyrin-G Deletion Triggers Bipolar-Like Brain Changes in Adult Mice
Understanding why bipolar disorder can emerge or worsen in adulthood — long after neural development is complete — has…
Studies
Malaria Parasite Enzyme TPK Identified as Dual Drug Target and Resistance Marker
Antimalarial drug resistance remains one of the most urgent threats to global infectious disease control, and…
Studies
Retinal VEGF Surges Within Minutes via HIF-1α-Independent Oxygen Pathway
The prevailing model of how tissues respond to low oxygen has a critical blind spot: it assumes the body needs hours…
Studies
Low ISM2 Protein in Early Pregnancy Predicts Preeclampsia and Fetal Growth Failure
Two of obstetrics' most dangerous complications — preeclampsia and fetal growth restriction — have long lacked…
Studies
Malaysian Men Face 68% Higher Cardiovascular-Oral Cancer Dual Burden Than Women
When two major non-communicable diseases share the same lifestyle risk factors — tobacco and alcohol — their combined…
Studies
Human-Exclusive microRNA Governs Synapse Formation Timing via Mitochondrial Control
What makes the human brain develop so slowly — and so powerfully — compared to other primates has been one of…
Studies
All-Oral AML Regimen Achieves 47% Complete Response in Elderly Patients
For older adults with acute myeloid leukemia, the difference between treatment and no treatment has long been…
Studies
Pan-RAS Inhibitor Brain Penetration Jumps 20-Fold With Efflux Transporter Block
For the roughly 30% of KRAS-mutant lung cancer patients who develop brain metastases, the blood-brain barrier is not…
Fitness
Single Walking Session Reshapes Executive Function Brain Patterns Differently Across Ages
Understanding how a single bout of moderate exercise influences the aging brain's executive circuitry matters…
Studies
Social Vulnerability Index Explains Part of Black-White Ovarian Cancer Survival Gap
Ovarian cancer is already one of the most lethal gynecologic malignancies, but not all patients face equal odds — and…
Nutrition
Animal Data Shows Time-Restricted Feeding Extends Lifespan When Combined With Caloric Restriction
The timing of food intake is emerging as a variable nearly as consequential as what or how much is eaten — a shift…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.