Nutrition
Early-Life Sugar Restriction in First 1000 Days Cuts Lifetime Dementia Risk
The first thousand days of life — from conception through age two — have long been considered a critical developmental…
Studies
CKM Syndrome Linked to Early Arterial Damage in 80% of Young Adults
Cardiovascular disease rarely announces itself — it builds silently over decades, starting with metabolic dysfunction…
Studies
Cochrane Review: E-Cigarettes Outperform Patches and Gum for Smoking Cessation
Smoking remains the leading preventable cause of premature death globally, and the persistent gap between quit…
Studies
Bariatric Surgery Remodels Abdominal—Not Gluteal—Fat Proteome Over 12 Months
A randomised, prospective 12-month study in women with obesity combined proteomics, metabolomics, advanced imaging…
Nutrition
App-Based Coaching Matches Dietitian Care for Fatty Liver in 297-Person RCT
In a 12-month randomised controlled trial of 297 adults with metabolic dysfunction-associated steatotic liver disease…
Studies
438,000-Veteran Study: Moderate Alcohol Cuts Heart Risk, Raises Cancer Risk
In 438,442 U.S. veterans followed from 2011 to 2024 in the Million Veteran Program, moderate alcohol consumption…
Nutrition
Higher MUFA Density Raises Colorectal Cancer Risk 46% in Postmenopausal Women
Using metabolomic serum biomarkers calibrated against a controlled feeding study (n=153) in the Women's Health…
Nutrition
Cutting Dietary Fructose Drops Novel Glycation Biomarker by 20% in Overweight Adults
Restricting dietary fructose significantly reduces serum glucoselysine (GL), a fructose-specific glycation product, in…
Fitness
Bariatric surgery boosts VO2 max despite muscle loss in all groups
In a longitudinal cohort of 1,022 adults undergoing metabolic bariatric surgery (MBS), fat-free mass (FFM) loss varied…
Nutrition
Omega-3 Depletion Predicts Plaque Rupture Risk Despite Low LDL in 263K Adults
A specific fatty acid phenotype defined by omega-3 depletion and elevated omega-6/omega-3 ratio predicted structurally…
PREPRINTSupplements
Apigenin Extends Worm Lifespan and Shields Against Alzheimer's Proteins via Redox Signalling
Chronic apigenin exposure extended median lifespan in wild-type C. elegans and improved multiple healthspan markers…
PREPRINTStudies
GLP-1 Drugs Skew to Younger, Heavier Older Adults — Sicker Patients Left Out
Among 58,754 adults aged 65 or older with type 2 diabetes treated at a regional US healthcare system between 2018 and…
PREPRINTFitness
Swapping 30 Min of Sitting for Moderate Exercise Cuts AFib Risk 20%
Across 91,873 adults in the UK Biobank and US REGARDS cohorts tracked by accelerometry, replacing 30 minutes of daily…
PREPRINTNutrition
Virtual Dietitian Visits Cut LDL 14 mg/dL and HbA1c 1.4 Points in 18,965 Patients
Across 18,965 adults enrolled in a national virtual medical nutrition therapy (vMNT) platform, six months of…
PREPRINTWellbeing
Mental Stress Triples Heart Attack Risk in Women Post-MI, Black Women Hit Hardest
Among 602 adults (mean age 51; 46% women) studied within eight months of a premature myocardial infarction, mental…
Studies
Bariatric Surgery Suppresses Oncogenic Pathways Across Tissue, Blood, and Metabolome
A systematic multi-omics analysis pooling 22 transcriptomic, 6 proteomic, and 5 metabolomic datasets from metabolic…
Nutrition
Healthy Plant-Rich Diets Linked to 31% Better Smell Function in 6,690 Adults
Among 6,690 adults in the CHRIS cohort study, higher adherence to five established healthy dietary patterns…
Nutrition
5:2 Fasting Rebuilds Muscle and Liver in MASLD Mice via Gut-Bile Axis
In male C57BL/6J mice fed a 45% high-fat diet for 14 weeks to induce metabolic dysfunction-associated steatotic liver…
Studies
GLP-1 Drugs Cut Post-Sepsis 90-Day Mortality 19% vs. SGLT2 Inhibitors
Among nearly 24,000 propensity score-matched adults with type 2 diabetes who developed sepsis, those previously taking…
Fitness
10,000 Steps, 48-Min MVPA, 7.8-Hr Sleep Linked to Lower Disease Risk
Analyzing 11.8 million person-hours of wrist accelerometer data from 70,473 UK Biobank participants followed for up to…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.