Longevity
ACE2 Overexpression Protects Against Cardiac Aging Injury in K18-hACE2 Transgenic Mice
Most adults know ACE2 as the receptor SARS-CoV-2 exploits to enter cells, but this enzyme has a far older and more…
Studies
Oncolytic Viruses Reshape Tumor Immunity via Two-Pronged Kill Mechanism
As global cancer incidence approaches 30 million new annual cases by mid-century, conventional oncology's persistent…
Longevity
Aging Stem Cells Hijack Immune Memory to Drive Chronic Inflammation via SIRT3 Loss
Chronic low-grade inflammation — inflammaging — has long been recognized as a root driver of age-related disease, but…
Studies
Five HIV Reservoir Phenotypes Linked to Distinct Inflammatory Immune Signatures
For the roughly 39 million people living with HIV globally, viral suppression via antiretroviral therapy is no longer…
Studies
Hormone Therapy Benefit After Prostate Surgery Unchanged by Pathologic Risk Score
For men with recurrent prostate cancer after surgery, a persistent clinical question has been whether the severity of…
Studies
GLP-1 Drug Cessation Triggers Metabolic Adaptations That Accelerate Weight Regain
For the millions now using semaglutide or tirzepatide, the harder question isn't how to lose weight — it's what…
Studies
Repeated Embryo Freezing Cycles Progressively Compromise Viability and Fetal Growth
For the millions of people navigating IVF and preimplantation genetic testing, a critical but underexplored question…
Studies
9-Gene cfDNA Methylation Classifier Distinguishes Malignant Pulmonary Nodules Noninvasively
Pulmonary nodules are among the most common incidental findings on chest imaging, yet determining whether they are…
Fitness
Smartphone JITAIs Show Early Promise Reducing Sedentary Time in Chronic Disease
For the estimated 60% of adults managing at least one chronic condition, the gap between knowing they should move more…
Studies
RNA-Binding Protein MBNL1 Drives Leukemia via Direct DNA Enhancer Hijacking
A previously unrecognized molecular mechanism in an aggressive blood cancer subtype may open a new class of…
Fitness
Prolonged Uninterrupted Sitting Associated with 9% Higher Cancer Mortality Risk Per Hour
How sedentary time is structured — not just its total duration — may matter as much as how much time is spent sitting…
Studies
SGLT2 Inhibitors Associated With ~50% Lower All-Cause Mortality in Endometriosis-T2D: Propensity-Matched Study
Endometriosis has long been dismissed as a localized gynecological condition, but its identity as a systemic…
Supplements
Niosomal Gallic Acid Reduces Fatty Liver Markers Via Dual Pathway Modulation in Rats
Nonalcoholic fatty liver disease remains one of the most underappreciated consequences of obesity, and the chronic…
Studies
Oseltamivir Linked to Lower ICU Risk in Hospitalized Children Across Nine Flu Seasons
For parents and pediatricians navigating influenza season, a critical question has lingered: does antiviral treatment…
Studies
LRRK2 Parkinson's Kinase Maps to Centrosome Network via Proximity Proteomics
Understanding how a key Parkinson's disease protein organizes its cellular partnerships could reshape how researchers…
Studies
Artemisinin Resistance Markers Spreading in East Africa, Spatiotemporal Model Reveals
The quiet erosion of malaria's front-line treatment is one of global health's most consequential threats — and…
Studies
Breast Cancer Organoids Predict Chemotherapy Resistance and Reveal Rescue Combinations
For the roughly 15–20% of breast cancer patients whose tumors resist standard chemotherapy, the search for viable…
Studies
Magnesium Sulfate and Cooling Therapy Anchor Evidence-Based Neonatal Brain Protection
Cerebral palsy, cognitive impairment, and sensory disabilities remain among the most consequential outcomes of…
Studies
FMF Patients Face Elevated 20-Year Risk Across Multiple Autoimmune Conditions
For the estimated millions carrying pathogenic MEFV variants worldwide, the clinical picture may extend well beyond…
Studies
Iptacopan Halves Kidney Function Decline Rate in Phase 3 IgA Nephropathy Trial
For the roughly 1 in 500 adults who carry an IgA nephropathy diagnosis, the trajectory toward dialysis or transplant…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.