PREPRINTStudies
96% Drop in China's Child Respiratory Deaths Unlinked to Warming After Detrending
China's childhood lower respiratory infection mortality collapsed from 330,194 deaths in 1990 to 12,098 in 2021—a…
PREPRINTStudies
Summer Alcohol Injuries Peak Predictably in Adults 25–64, But Not Elderly Women
Analysis of 45,876 alcohol-associated emergency department visits (weighted national estimate: ~2.09 million) drawn…
PREPRINTLongevity
Guatemala's First Population-Based Aging Study Targets 40% Indigenous Maya Population
A pilot cross-sectional household survey of up to 600 adults aged 40 and older in Tecpan, Guatemala has established…
PREPRINTStudies
59% Publication Rate at ADA Sessions Reveals Persistent Null-Result Suppression
Among 541 abstracts presented at the 2018 American Diabetes Association Scientific Sessions, only 59.3% were…
PREPRINTFitness
Correcting Accelerometer Errors Reveals 56% Stronger CVD Protection From Daily Movement
Applying a novel statistical pipeline — combining accelerated failure time models, spline regression, and…
Studies
Major 2026 Guidelines Unify Obesity, Kidney Disease, and Heart Risk Management
For decades, cardiology, nephrology, and endocrinology operated in largely separate clinical silos — treating heart…
Studies
CDK2 Inhibition Boosts Immunotherapy Efficacy via BRD4-Mediated Transcriptional Reprogramming
The discovery that a well-known cell-cycle kinase doubles as a transcriptional gatekeeper — and that blocking it could…
Studies
Workplace First Responders Score High on CPR Knowledge But Gaps Persist Across Departments
Sudden cardiac arrest kills within minutes, and the first person on scene — not a paramedic — is usually the one who…
Nutrition
NLP Analysis Reveals Income-Driven Gaps in Global Dairy Dietary Guidance
How a country frames its dietary advice may reveal as much about its economic standing as its nutritional science. A…
Studies
PARP1 Enzyme Drives Neuropathic Pain via Glial Redox Reprogramming
Chronic neuropathic pain remains one of the most therapeutically resistant conditions in medicine, partly because its…
Longevity
Hippo-IGF2 Axis Controls Liver Size and Rescues Age-Impaired Regeneration
A newly characterized Hippo-IGF2 signaling axis governs both developmental organ sizing and regenerative capacity. In…
Fitness
Resistance Training Preserves Tongue Motor Function in Low-Aerobic-Capacity Aging Rats
In 18–24-month-old rats selectively bred for high (HCR) or low (LCR) aerobic capacity, resistance exercise training…
Longevity
Midlife GH Receptor Knockout Extends Lifespan and Feminizes Male Liver Transcriptome
Ablating the growth hormone receptor (Ghr) in 12-month-old mice — equivalent to roughly midlife — extended lifespan in…
Studies
Epigenetic Reprogramming of Motor Neurons Amplifies Stroke Rehabilitation Outcomes in Mice
One of the most stubborn barriers to stroke recovery is not the injury itself, but the aging brain's diminished…
Studies
Clopidogrel Alone Matches Dual Antiplatelet Therapy After Stent Implantation
For the millions of adults living with coronary artery disease and a drug-eluting stent, the question of how long to…
PREPRINTStudies
Temple Wearable Tracks Brain Blood Flow With r=0.80 vs Gold-Standard Doppler
A temple-worn optical wearable device, outputting a proprietary dimensionless Brain Flow index, correlated strongly…
PREPRINTStudies
Bayesian Reanalysis of 60,619 Patients Challenges Prasugrel's Superiority After Heart Attack
A Bayesian network meta-analysis of 19 randomized controlled trials encompassing 60,619 patients undergoing PCI after…
PREPRINTLongevity
AI Reconstructs 3D Heart Geometry From ECG Alone in 71,000 Patients
A conditional flow-matching model called visionECG, trained on 71,132 paired ECG and cardiac mesh sequences from the…
PREPRINTLongevity
Novel MVX Biomarker Links Metabolic Inflammation to 12% Higher Mortality Risk in 218,635 Adults
In a prospective analysis of 218,635 UK Biobank participants followed for a median 14.4 years, each standard deviation…
PREPRINTLongevity
Urine Peptide Clock Predicts Death Risk with 48% Higher Hazard Per SD
A urinary peptidomic biological age clock built from capillary electrophoresis-mass spectrometry data across 17,000+…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.