Nutrition
Critical Care Nutrition Myths for Children Challenged by JAMA Analysis
Getting nutrition right for mechanically ventilated children in the ICU is one of pediatric critical care's most…
Wellbeing
Poor Sleep Identified as Modifiable Risk Factor Directly Linked to Obesity
The relationship between sleep and body weight has long been treated as secondary in clinical practice, with diet and…
Studies
Most Older Adults May Safely Stop Levothyroxine Without Thyroid Relapse
For the millions of adults over 60 who take a daily thyroid hormone pill—often started decades earlier—the question of…
Studies
Structured Deprescribing Protocol Enables Levothyroxine Discontinuation in Older Adults
The assumption that thyroid hormone replacement is a lifelong commitment may be more assumption than fact — at least…
Studies
MPO Inhibitor Mitiperstat Fails to Improve HFpEF Outcomes in Phase 2b Trial
For the millions living with heart failure with preserved or mildly reduced ejection fraction — a condition…
Studies
Inhaled Gene-Silencing Therapy Safely Cuts Lung Inflammation Marker in Humans
For the millions living with chronic pulmonary conditions driven by persistent inflammation, the therapeutic toolkit…
Wellbeing
Older Adults Spend 4.3 of Final 23 Years Lonely — Modifiable Factors Cut Risk
Loneliness is not merely an emotional discomfort — it is a measurable state that consumes a predictable portion of…
Longevity
Long-Term Traffic Noise Linked to Six Distinct Cardiovascular Disease Pathways
Urban living carries hidden cardiovascular costs that extend well beyond air pollution and sedentary behavior. A…
Studies
IPV-Linked HIV Burden Quantified Globally; Funding Cuts Forecast Deadly Reversals
Decades of hard-won progress in HIV mortality and incidence reduction may be unraveling — and for women in particular…
Studies
Network Meta-Analysis Ranks Best Drug Options for Antipsychotic Weight Gain
Antipsychotic-induced weight gain sits at the intersection of two major health crises: the undertreatment of serious…
Studies
AI Agent MIRA Surpasses Physicians in EHR-Integrated Diagnostic Accuracy
The boundary between clinical decision support and autonomous clinical action has just been meaningfully crossed. For…
Studies
AI Agent MIRA Surpasses Physicians in Diagnostic Accuracy Within EHR Systems
The assumption that artificial intelligence in medicine would remain a background assistant — surfacing information…
Studies
AI Reads Single-Lead ECG to Detect Four Heart Failure Subtypes Simultaneously
Silent cardiac dysfunction — particularly the notoriously difficult-to-diagnose heart failure with preserved ejection…
Studies
Advanced Immunotherapies Severely Compromise Vaccine Efficacy in Rheumatic Disease Patients
For the millions of adults living with autoimmune rheumatic diseases, the calculus around vaccination is far more…
Studies
Novel Lipid Nanoparticle Variant Boosts mRNA Vaccine Safety and Potency
The delivery mechanism of mRNA vaccines has quietly been one of the most consequential—and least discussed—variables…
PREPRINTLongevity
Belly Fat Drives Lacunar Stroke 30% Via Blood Pressure, MR Study Finds
Using two-sample Mendelian randomization mediation analysis across 16 candidate biomarkers, abdominal…
PREPRINTLongevity
Copper Cell-Death Genes Show No Causal Link to Heart Disease Risk
Despite striking transcriptional activation of cuproptosis and copper-transport genes in atherosclerotic plaque…
PREPRINTLongevity
Metabolically Dysfunctional Lean Individuals Face Same CAD Risk as Obese, Via Different Pathways
A two-sample Mendelian randomization study using 60,801 coronary artery disease cases from CARDIoGRAMplusC4D found…
PREPRINTLongevity
Only 0.9% Tested: Lp(a) Above 125 nmol/L Drives 67% Higher PCI Risk
Across 687,780 primary prevention patients in the PITT-LIPID real-world registry, only 6,340 (0.9%) ever received…
PREPRINTFitness
Seated Heel-Raises Every 10 Minutes Cut Stroke Patients' Blood Pressure Rise by 42%
Among 15 chronic stroke patients (mean age 69.3 years), three hours of uninterrupted sitting elevated central systolic…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.