Studies
Severe Mental Illness Linked to 133% Higher Chronic Kidney Disease Odds
Kidney disease rarely appears on lists of psychiatric comorbidities, yet the organ-level toll of conditions like…
Studies
Silent Strep Throat Exposures Build Lasting Protective Immunity Without Symptoms
The longstanding assumption that you need a symptomatic infection to build meaningful immunity is being quietly…
Studies
Childhood Trauma Linked to Lower Oxytocin and Greater Metabolic Risk in Schizophrenia
For people living with schizophrenia, metabolic syndrome is already a leading driver of reduced life expectancy — yet…
Studies
Oxidative Stress Triggers Skin Cell Adhesion Collapse in Darier Disease
For people living with heritable skin conditions that flare unpredictably, understanding why symptoms appear when they…
Studies
Network Meta-Analysis Ranks Seven Bipolar Depression Treatments With Moderate-to-Good Confidence
Bipolar depression remains one of psychiatry's most stubborn therapeutic puzzles — patients spend roughly half their…
Studies
448,935-Cell Pancreatic Atlas Unifies Fragmented T1D Single-Cell Data
Understanding why insulin-producing beta cells die in type 1 diabetes has long been hampered by a fragmented data…
Studies
ASTRO Issues Updated Comprehensive Radiation Guidelines for Pancreatic Cancer Treatment
Pancreatic cancer remains one of oncology's most lethal diagnoses, with five-year survival rates still hovering near…
Fitness
Home-based HIIT During Neoadjuvant Chemotherapy Associated with Favorable Responses and Tumor Microenvironment Remodeling in Breast Cancer
For breast cancer patients undergoing chemotherapy, the tumor microenvironment — not just systemic drug exposure — may…
Studies
Renaming Low-Risk Prostate Cancer 'Lesion' Shifts Patient Treatment Preferences
How a condition is named can be just as consequential as how it is treated — particularly in prostate pathology, where…
Studies
Review Examines Tiered Multimodal Protocols to Reduce Opioid Use After Knee Replacement
Knee replacement surgery sits at a crossroads of two public health crises: the opioid epidemic and the rapid aging of…
Studies
Triple Hormone Agonist Retatrutide Cuts HbA1c and Weight in Phase 3 Trial
For the millions of people with early-stage type 2 diabetes inadequately managed by lifestyle alone, the therapeutic…
Supplements
Amylin Analogs Cagrilintide & Petrelintide May Outperform GLP-1s on Tolerability
Amylin, a pancreatic β-cell hormone co-secreted with insulin, acts on central nervous system circuits to produce…
Fitness
High GLP-1 Discontinuation Rates Highlight Need for Post-Treatment Strategies: Narrative Review on Exercise for Lean Mass and Rebound Mitigation
When patients stop incretin-based medications like semaglutide or tirzepatide, they regain an average of 5.6 kg within…
Supplements
Resveratrol Nanoparticles Achieve 7-Fold Bioavailability Boost Via Lymphatic Route
Nanostructured lipid carriers loaded with resveratrol (RES-NLCs) delivered a 2.3-fold increase in peak plasma…
Studies
714 Mother-Infant Pairs Reveal Maternal Gut Strain Transmission and Eczema Association in Lifelines NEXT Cohort
Metagenomic sequencing of 4,526 longitudinal fecal samples from 714 Dutch mother-infant pairs (Lifelines NEXT cohort)…
Studies
Systematic Review Links Alcohol to Reduced Butyrate and Tryptophan Metabolites Across 12 Human and Primate Studies
Across 12 studies spanning humans and non-human primates, alcohol exposure consistently disrupted several gut…
Longevity
Gut Microbiome Shares Overlapping Dysbiosis Signals Across Stroke, Heart Attack, and Aging
Across an internal ischemic stroke cohort and several public datasets spanning myocardial infarction, stroke, and…
Supplements
Four Bioactive Compounds Target Complementary Aging Pathways via Distinct Molecular Mechanisms
Four mechanistically distinct natural compounds — spermidine (autophagy via EP300 inhibition), fisetin (senolysis via…
Longevity
Heart Aging Reframed: 4 Organ Axes Drive Cardiac Senescence via TMAO, EVs, Myokines
Cardiac senescence emerges from at least four pathological communication axes — epicardial adipose tissue-heart…
Longevity
Liver SIRT6 Loss Cuts Female Lifespan 17.6% via SULT1E1-Estrogen Collapse
Female mice with hepatocyte-specific SIRT6 knockout suffered a 17.6% reduction in median lifespan alongside visceral…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.