Studies
Metformin and UDCA Show No Benefit Over Placebo for Long COVID
Two promising therapeutic candidates for long COVID have failed to demonstrate meaningful benefits in the largest…
Wellbeing
First Trimester Air Pollution Exposure Linked to ADHD Symptoms in Children
Environmental neurotoxicity during pregnancy may be shaping the attention and behavioral challenges millions of…
Studies
GSDME Protein Pathway Reshapes Lung Cancer Immune Suppression Mechanisms
A fundamental shift in cancer immunotherapy may be emerging as scientists uncover how a specific cellular death…
Studies
CBD Blocks Critical Heart Rhythm Channels Through Two Separate Mechanisms
Cannabis-derived CBD's growing therapeutic use faces a potential cardiac safety concern that could affect millions of…
Studies
AI Medical Studies Lack Real Clinical Data Despite Research Boom
The explosive growth of artificial intelligence in healthcare research may be built on shaky foundations. While…
Studies
Base Editing Therapy Reduces LDL Cholesterol in Genetic Hypercholesterolemia Trial
Genetic cholesterol disorders may become treatable with permanent gene editing rather than lifelong medication…
Studies
PCSK9 Base Editing Shows Promise for Inherited High Cholesterol
Gene editing technology may finally offer a permanent solution for the estimated 34 million people worldwide living…
Longevity
Gut Microbiome Transplants Restore Ovarian Function in Aging Female Mice
The discovery that aging ovaries might be rejuvenated through gut microbiome intervention opens a transformative…
Longevity
Depression Accelerates Brain Aging Through Measurable Protein Changes
The connection between depression and premature aging now has molecular precision, with potentially transformative…
Longevity
Killifish Aging Atlas Maps Tissue-Specific Biomarkers Across Vertebrate Lifespan
Finding reliable biomarkers of aging remains one of the most challenging puzzles in longevity research, with most…
Longevity
Biomarker Consortium Tackles Key Challenge in Anti-Aging Drug Development
The translation of promising anti-aging compounds from laboratory to clinic faces a critical bottleneck: the absence…
Studies
3D Lab System Models Human Embryo-Uterine Interaction Through Day 14
Understanding how human embryos interact with the uterine environment during the critical first two weeks after…
Studies
Conserved Appetite-Regulating Neurons Identified in Zebrafish and Mice
Understanding how vertebrate brains evolved to control hunger could unlock more effective treatments for obesity and…
PREPRINTStudies
Standard Risk Factors Miss 24% of Heart Transplant Candidates with Atherosclerosis
Among 167 heart transplant candidates analyzed via computed tomography angiography, 24% had no traditional…
PREPRINTLongevity
Tachycardia Linked to 3.6X Higher All-Cause Mortality Risk, Partially Via Silent Cardiac Damage
Analysis of 7,152 cardiovascular disease-free adults from NHANES III reveals that resting tachycardia (≥100 bpm)…
PREPRINTLongevity
10 Modifiable Risk Factors Associated With Brain Atrophy in 38,414 Adults
Analysis of 38,414 older adults reveals that accumulating modifiable risk factors—including hypertension, diabetes…
PREPRINTLongevity
FAXAge Trial Tests Exercise Plus Fasting on DNA Aging in 240 Seniors
The FAXAge trial will randomize 240 healthy adults over 65 into four groups—exercise alone, time-restricted feeding…
PREPRINTWellbeing
Under-Mattress Sensors Predict Next-Day Dementia Agitation Episodes
Contactless under-mattress sensors successfully predicted next-day agitation episodes in dementia patients across 73…
Studies
Rectal Mucus Analysis Detects Early Colorectal Cancer Without Colonoscopy
The prospect of detecting colorectal cancer without the expense, discomfort, and bowel preparation required for…
Studies
Poor Childhood Dental Health Linked to Up to 45% Higher Adult Heart Disease Risk
The window for cardiovascular protection may open much earlier than previously recognized, with dental health in…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.