Genetic Architecture of Coronary Disease Reveals New Therapeutic Targets
Genome-wide association studies have identified over 300 genetic loci linked to coronary artery disease risk, with poly…
Genome-wide association studies have identified over 300 genetic loci linked to coronary artery disease risk, with poly…
Enlicitide demonstrated a 60% reduction in LDL cholesterol levels compared to placebo in a phase 3 randomized controlle…
Digital health literacy emerges as a critical vulnerability among aging populations, potentially undermining evidence-b…
The ability to navigate health information online becomes increasingly critical as digital platforms replace traditiona…
A comprehensive WHO analysis examining 30 modifiable risk factors reveals that 40% of global cancer cases stem from pre…
A comprehensive WHO analysis examining 30 modifiable risk factors reveals that 40% of global cancer cases stem from pre…
Stem cells lose their regenerative potency through five interconnected molecular pathways that accelerate with age. Cel…
African trypanosomes utilize a sophisticated molecular switch involving variant surface glycoproteins (VSGs) to continu…
Scientists achieved precise control over silica nanostructure formation by using DNA scaffolds to direct positively cha…
Kv6.4, a voltage-gated potassium channel subunit, selectively regulates the firing patterns of parvalbumin-positive int…
A computational framework successfully distinguishes between benign and pathogenic single amino acid substitutions in p…
This issue of the Proceedings of the National Academy of Sciences (PNAS) presents a collection of research articles cov…
Wang and colleagues identified mitoxyperilysis, a previously unrecognized cell death mechanism triggered when immune st…
Analysis of UK Biobank participants reveals a precise threshold where vigorous exercise shifts from cognitive protectio…
Metastatic cancer cells actively acquire mitochondria from surrounding immune cells through a previously uncharacterize…
Troha et al. discovered that kidneys actively filter pro-inflammatory cytokines from circulation and excrete them in ur…
Mouse experiments reveal that bile acid pool size and composition directly regulate intestinal fat absorption through a…
Platinum chemotherapy triggers cellular senescence in ovarian and lung cancer cells, paradoxically promoting malignancy…
Researchers developed molecular aging clocks to measure the biological versus chronological age of individual neuron ty…
Researchers have developed methods to selectively eliminate specific populations of senescent cells while preserving th…
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