Studies
Finerenone Slows Kidney Decline in Non-Diabetic CKD Patients
Chronic kidney disease affects roughly 850 million people worldwide, yet most disease-modifying therapies have been…
Studies
Finerenone-Empagliflozin Combo Cuts Blood Pressure Beyond Either Drug Alone
For the roughly one in three adults with both type 2 diabetes and chronic kidney disease who struggle to reach blood…
Studies
S1P Receptor Agonism Cuts Edema and Inflammation in Donor Lungs During Perfusion
Lung transplantation is severely constrained by organ scarcity — and a significant fraction of otherwise viable donor…
Studies
Smart Nanoparticle Dismantles Radiation Therapy's Hidden Immune Shield in Tumors
Radiation therapy is one of oncology's most foundational tools, yet a paradox has quietly undermined its…
Studies
Global TB Burden Mapped Across 204 Nations: MDR-TB Progress Lags Far Behind WHO Targets
Tuberculosis remains one of the most consequential infectious disease failures of the modern era — not because…
Studies
GLP-1 Drugs Show No Added Anesthetic Risk in 196 Body-Contouring Patients
Among 196 patients undergoing high-definition lipoabdominoplasty under general anesthesia, those taking semaglutide or…
Fitness
12-Week Resistance Training Cuts Brain Lactate 0.78 SD, Boosts Sleep Efficiency in Over-64s
Twelve weeks of explosive lower-body resistance training three times weekly produced measurable neurometabolic and…
Supplements
Dual-Compartment Yeast Engineering Yields 552 mg/L Resveratrol via Peroxisome Factory
A dual-compartment metabolic engineering strategy simultaneously activated resveratrol biosynthesis in both the…
Studies
Gut Bacteria Enterocloster and Bacteroides_H Predict HIV Neuropathy with 83% Accuracy
In a cross-sectional cohort of 218 participants—61 HIV-positive individuals with distal sensory polyneuropathy (DSP)…
Longevity
Gut Metabolites Ceramide & 24-Hydroxycholesterol Linked to Accelerated Brain Aging Index
Across three cohorts totaling 1,462 adults, a Bayesian ridge regression model applied to resting-state fMRI data…
Longevity
NAD+ Depletion Drives CD8+ T Cell Senescence via cGAS-STING in Colitis
Senescent CD8+ T cells accumulate in ulcerative colitis (UC) mucosa through a discrete metabolic cascade: NAD+…
Longevity
101 Species Living 250+ Years Share 3 Core Longevity Mechanisms
Among 101 multicellular species capable of living 250 years or longer — 11 animals and 90 plants — a systematic survey…
Studies
GLP-1 Drugs Show Weight-Independent Benefits Across 12 Major Disease Systems
The assumption that obesity drugs work solely by shrinking fat mass is being systematically dismantled — and the…
Studies
Ferritin Nanoparticle Vaccine Clears Amyloid Plaques, Rescues Memory in Primate-Validated Model
For decades, active immunotherapy against amyloid-β has been a tantalizing but elusive strategy for Alzheimer's…
Studies
KDIGO Conference Maps B-Cell Therapy Efficacy Across Six Kidney Diseases
For patients living with autoimmune kidney disease, the difference between preserving kidney function and progressing…
Studies
Pragmatic Trial Design Cuts NSCLC Protocol Complexity by 65–83 Percent
Cancer clinical trials are notorious for their staggering operational burdens—dense protocols, exhaustive data fields…
Studies
Anticorrelated Brain Network Integrity Predicts Recovery Trajectory After Traumatic Brain Injury
Predicting who will recover meaningfully after a traumatic brain injury has long been one of neurology's most…
Studies
Single-Cell Mapping Reveals How Stress Response Drives Cognitive Decline
Understanding why certain brain cells become dysfunctional in cognitive disorders has long been hampered by the…
Studies
Hox Proteins Anchor Autophagy Genes at Nuclear Periphery to Silence Them
Understanding how cells suppress autophagy — the cellular recycling program intimately tied to aging, cancer, and…
Studies
Medicare Data Challenges mRNA Vaccine Boost to Cancer Immunotherapy Claims
The intersection of COVID-19 vaccination and cancer treatment has generated intense interest among oncologists and…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.