Studies
AI Pipeline Identifies GPNMB as Cross-Cancer CAR T-Cell Target
The central challenge of CAR T-cell therapy has never been engineering the immune weapon itself — it has been knowing…
Studies
Foodborne Parasites Still Cause Nearly 5 Million Lost Life-Years Annually
Parasitic infections transmitted through food remain a vastly underappreciated contributor to global disease burden…
Wellbeing
Psychotherapy Shows Large PTSD Effect in Adolescent Sexual Abuse Survivors
Trauma-focused psychotherapy for adolescents who have experienced penetrative sexual abuse remains severely…
Wellbeing
Emotion Regulation Deficits Strongly Associated with Insomnia Severity in Adults With ADHD
Sleep problems in ADHD are often attributed to hyperarousal or circadian misalignment, but a growing body of evidence…
Studies
Salivary HHV-6 Viral Load Correlates With Long COVID Symptom Severity Scores
The persistent, often debilitating symptom burden of Long COVID remains mechanistically poorly understood, yet…
Studies
DECISION Trial: Low-Dose Digoxin Misses Primary Endpoint in 1,001-Patient Heart Failure RCT
Heart failure management has changed dramatically over the past three decades, yet digoxin — one of medicine's oldest…
PREPRINTLongevity
Irregular Sleep Linked to Higher Mortality Risk in Men: UK Biobank Study Suggests Sex Differences
Analyzing 506,582 person-days of accelerometer recordings from 73,647 UK Biobank participants followed for over…
PREPRINTStudies
235,571-Person BRFSS Analysis Quantifies Diabetes, Smoking, and Income as Top Stroke Predictors
A pooled cross-sectional analysis of 235,571 U.S. adults from the 2021–2023 Behavioral Risk Factor Surveillance System…
PREPRINTWellbeing
Untreated Hearing Loss Linked to Higher Depressive Symptoms and Reduced Friend Contact in Older Adults
Among 2,049 Black and White adults aged 70–79 in the Health, Aging, and Body Composition Study, objective hearing loss…
PREPRINTLongevity
355K-Person UK Biobank Multi-Omic Study Maps CKM Syndrome Stages to CVD via Statistical Mediators
Across 355,724 UK Biobank participants followed for a median 13.5 years, a multi-omic analysis mapped…
PREPRINTLongevity
10 Plasma Immune Markers Inversely Linked to Alzheimer's Tau/Amyloid Ratio, With Sex Differences Emerging
In a cross-sectional cohort of 261 participants from the Cleveland Clinic Lou Ruvo Center Biobank, ten plasma…
Longevity
GLP-1 Incretin Therapy Associated With 54% Lower Alzheimer's Incidence in 57,800-Patient EHR Study
In a propensity-score matched cohort of 57,802 adults aged 50+ with documented Alzheimer's risk factors drawn from 29…
Longevity
Mediterranean Lifestyle Associated with 51% Lower CVD Death Risk in Type 2 Diabetics
Among 3,612 UK Biobank participants with type 2 diabetes followed for up to 12.1 years, those in the highest quartile…
Studies
Beyond BMI: Endocrine Society Weighs New Obesity Classification Framework's Clinical Trade-offs
How obesity is defined shapes who gets treated, when, and with what urgency — making the Lancet Diabetes &…
Fitness
Self-Balancing Exoskeleton Shows Safety and Usability Gains in Complete Paraplegia
For the roughly 300,000 Americans living with spinal cord injury, the gap between laboratory promise and real-world…
Longevity
UC-MSC Secretome Suppresses MMP-13 and ADAMTS-5 in Osteoarthritis Models
The secretome of umbilical cord-derived mesenchymal stem cells (UC-MSCs) — encompassing soluble paracrine factors and…
Studies
mPFC Neural Ensembles Show Stable Temporal Sequences During Decision-Making
Understanding how the brain converts incoming sensory signals into a deliberate choice has long been a central puzzle…
Studies
Ebola in Pregnancy: Maternal Survival Improves, But Neonatal Risk Remains Severe
For clinicians and public health professionals tracking emerging infectious threats, the intersection of Ebola virus…
Studies
Tirzepatide's Dual GIP/GLP-1 Action Shows Promise for MASH Fibrosis in Phase 2 Trial
Tirzepatide, a first-in-class dual GIP/GLP-1 receptor agonist, is generating clinical signals that extend well past…
Studies
Nirsevimab Cuts Infant RSV ICU Admissions by 57% in Belgian National Data
Respiratory syncytial virus has long been the leading infectious cause of infant hospitalization in high-income…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.