Studies
Genomic Profiling of 82,000 NSCLC Patients Reveals Actionable Mutations in One-Third
Precision oncology for lung cancer depends entirely on knowing a tumor's molecular fingerprint — yet large portions of…
Studies
PLCG2 Loss-of-Function Variants Associated with ~10-Fold Alzheimer's Risk, with Neuronal Knockdown Impairing Synapses and Elevating AD Hallmarks
Most Alzheimer's research focuses on amyloid clearance or inflammation, but a convergence of genetic and cellular…
Studies
Shift-Work Circadian Disruption Associated with Cardiometabolic Risk Markers in Philadelphia Nurses
For the roughly 20% of the global workforce engaged in shift work, the biological cost of misaligned schedules is…
Studies
Bundled Endoscopy Strategy Makes Gastric Cancer Screening Cost-Effective for High-Risk Groups
Gastric cancer kills roughly one million people annually worldwide, yet in the United States it is rarely screened for…
Wellbeing
A Companion's Phone Camera Impairs Your Memory as Much as Your Own
Most people instinctively know that burying their nose in a phone during a museum visit or dinner undermines their own…
Wellbeing
Air Pollution Linked to Divergent Cortical Thickness Patterns in Alzheimer's-Vulnerable Brain Regions
The assumption that air pollution uniformly harms the brain may be more complicated than assumed. New neuroimaging…
Studies
Wearable ECG-PPG Sensors Reconstruct ICU Blood Pressure Waveforms Non-Invasively
Invasive arterial lines remain a cornerstone of ICU monitoring, but they carry real risks — catheter-related…
Studies
Dual PD-1/VEGF Antibody Ivonescimab Extends Overall Survival in Squamous Lung Cancer
For the roughly 30% of non-small-cell lung cancer patients whose tumors have squamous histology — a subtype…
Studies
Dual PD-1/VEGF Bispecific Antibody Extends Survival Over Standard Immunotherapy in Lung Cancer
For the roughly 30% of non-small-cell lung cancer cases classified as squamous histology — a subtype historically less…
Longevity
Aging Microglia Dysfunction Linked to Chronic Pain via Kinin Receptor Pathway
Chronic pain in older adults is vastly underdiagnosed and undertreated, partly because its biological roots in aging…
Studies
PDE4D Enzyme Drives B Cell Invasion in Sjögren's Syndrome Glands
For the estimated four million Americans living with primary Sjögren's syndrome — a chronic autoimmune disease that…
Studies
Colorectal Tumors May Inadvertently Protect Arteries Via Arginine-T-Cell Axis
A counterintuitive intersection between oncology and cardiovascular biology is emerging: the metabolic environment…
Wellbeing
Youth Concussion Recognition in Sports: Role of Parents, Coaches, and Education Highlighted in Review
Sport-related concussion in young athletes is widely recognized as a risk, yet the scale of underreporting remains one…
Studies
p16-High Immune Cells Link COVID Vaccine to Broad Disease Tolerance
The longstanding assumption that surviving an infection depends almost entirely on killing pathogens faster than they…
Studies
Ugandan Malaria Parasite Evolves PX1 Haplotype Reducing Antimalarial Susceptibility
Antimalarial drug resistance has toppled treatment regimens before — chloroquine's collapse reshaped global malaria…
Studies
Artemisinin Resistance Mutations Reach 5% Prevalence Across East Africa
The quiet erosion of artemisinin's effectiveness — the backbone of malaria treatment worldwide — is now measurable at…
Studies
Two-Dose mRNA RSV Vaccine Shows Durable Immunogenicity in Transplant Recipients
For the estimated 500,000+ solid organ transplant recipients living in the United States, respiratory syncytial virus…
Fitness
Molecular Autopsy Reveals Hidden Arrhythmia Genes Behind Athlete Sudden Death
When a young athlete collapses and dies on a field, the tragedy extends far beyond one individual — because the…
Studies
GLP-1 Drugs Show Benefits Across 14 Conditions Beyond Weight Loss
The prevailing assumption that obesity drugs work simply by shrinking waistlines is increasingly difficult to defend…
Studies
AI Pipeline Identifies GPNMB as Cross-Cancer CAR T-Cell Target
The central challenge of CAR T-cell therapy has never been engineering the immune weapon itself — it has been knowing…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.