PREPRINTStudies
Microaxial Pump Beats ECMO on Cost-Effectiveness in Cardiogenic Shock: A$503K Per Survivor
A 30-day decision-analytic model comparing four mechanical circulatory support (MCS) strategies in acute myocardial…
PREPRINTLongevity
7T Cardiac MRI Maps Energy Deficits Segment-by-Segment in Heart Failure and Ischemia
Ultra-high-field 7T phosphorus magnetic resonance spectroscopic imaging (31P-MRSI) mapped the phosphocreatine-to-ATP…
PREPRINTFitness
12-Week Home Exercise Script Cuts Sarcopenia Prevalence in Obese Frail Seniors
A 12-week individualized, home-based physical activity prescription called PACE—combining functional resistance…
PREPRINTLongevity
29-Item Frailty Scale Captures 5 Dimensions Including Social and Environmental Risk
A newly developed 29-item Multidimensional Frailty Scale (MFS) demonstrated robust psychometric properties across five…
Studies
PET/MRI Fusion Detects Hidden Epilepsy Lesions Missed by MRI Alone in Children
For children trapped in cycles of drug-resistant seizures, the difference between a life-changing surgery and…
Supplements
GLP-1 Drugs Spare Muscle Mass But Long-Term Sarcopenia Risk Remains Unresolved
Incretin-based therapies — GLP-1 receptor agonists like semaglutide and tirzepatide, along with emerging…
Supplements
Semaglutide Regenerates Corneal Nerve Fibers in Diabetic Neuropathy Within 6 Months
A 57-year-old man with type 2 diabetes (HbA1c 6.6%, BMI 35.2 kg/m²) and established diabetic peripheral neuropathy…
Fitness
SCOPE Trial Tests Baduanjin vs. Resistance Training for Nursing Home Sarcopenia
A pragmatic cluster-randomized controlled trial — the SCOPE study — is enrolling 104 nursing home residents aged ≥75…
Studies
Exosome-Delivered Resveratrol Plus Blue LED Cuts Cavity Biofilm 85–89%
Encapsulating resveratrol (~63% efficiency) inside exosomes derived from human dental pulp stem cells (hDPSC-Exos) and…
Studies
46 Terpenoids Target AMPK/mTOR/NF-κB to Exploit Autophagy-Senescence in Lung Cancer
A systematic review of 46 structurally diverse terpenoids — spanning monoterpenoids, diterpenoids, triterpenoids, and…
Studies
HPV Vaccine Stalls at Fourth Year; Rural-Urban Gap Widens to 12 Points
A persistent and widening gap in adolescent HPV vaccination coverage carries direct implications for future cervical…
Studies
Dendritic Cells Gate CD8+ T Cell Entry Into Tau-Damaged Brains
The immune system's role in Alzheimer's disease has long been framed around microglia and innate immunity — but…
Longevity
Gut Microbiome Shifts in Aging May Accelerate Blood-Brain Barrier Decline
Cognitive decline in older adults may have a partial origin far from the brain itself — specifically, in the trillions…
Studies
IPV Drives Female HIV Vulnerability as Funding Cuts Threaten 2030 Progress
Decades of hard-won progress against HIV could unravel within years — and for women, a largely overlooked social…
Longevity
Six Proteomic Clocks Detect Anti-Aging Signals Inside a Phase 2a Drug Trial
Most drugs tested against age-related diseases are never evaluated for whether they also slow biological aging itself…
Studies
HIV's Brain Reservoir Drives Cognitive Decline Even Under Viral Suppression
For the millions of people living with HIV who have achieved undetectable viral loads, the assumption that brain…
Wellbeing
Social Media Amplifies Eating Disorder Risk for Competitive Athletes, Study Finds
Eating disorders remain disproportionately prevalent in athletic populations, yet the mechanisms driving and…
Studies
mRNA Nanoparticles Engineer Anti-Tumor Macrophages Directly Inside Solid Tumors
The longstanding frustration with CAR-T cell therapy in solid tumors — poor penetration, antigen escape, hostile…
Studies
Foodborne Pathogens Cause 666 Million Illnesses Annually, Africa Bears Sevenfold Mortality Gap
The global burden of foodborne illness remains staggeringly unequal — and a sweeping two-decade WHO analysis now…
Fitness
Wearables Improve Activity in Chronic Disease, But AI Evidence Remains Thin
For the roughly one-third of adults worldwide living with at least one chronic condition, the gap between what happens…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.