Studies
Phase III Trial: Dato-DXd Nearly Doubles Progression-Free Survival in Aggressive Breast Cancer
Triple-negative breast cancer carries one of oncology's bleakest prognoses precisely because it lacks the hormone…
Studies
Phase III SKYSCRAPER-01 Trial Fails to Confirm TIGIT Blockade Survival Benefit in Lung Cancer
One of the most closely watched questions in oncology immunotherapy has been whether blocking TIGIT — a second immune…
Studies
Enzyme YOD1 Accelerates Diabetic Kidney Damage via KEAP1 Stabilization Pathway
Diabetic kidney disease remains the leading cause of end-stage renal failure worldwide, and therapeutic options that…
Studies
Conserved Allosteric Pocket Unlocks Small-Molecule Activation of Glucagon and GIP Receptors
As GLP-1-based therapies reshape metabolic medicine, the next frontier is developing orally bioavailable small…
Studies
Cancer Vaccine Landscape: Where Therapeutic Immunization Stands in 2026
Immunotherapy has fundamentally redrawn the oncology treatment map over the past decade, yet the specific promise of…
Studies
RNA Secondary Structure Emerges as Master Regulator of Gene Expression Therapeutics
Understanding how genetic information is read and translated may be about to undergo a significant conceptual upgrade…
Studies
Hidden Microproteins in Alzheimer's Cortex Regulate Microglial Energy Metabolism
The protein-coding landscape of the human brain has long been considered largely mapped, yet a vast class of tiny…
Longevity
Brain Atlas Uncovers 1,000+ Microproteins, One Linked to Alzheimer's Energy Deficit
For decades, the proteome of the aging brain has been charted with a blind spot: proteins smaller than roughly 100…
Studies
NAE1 Inhibition Suppresses Bone Loss via Iron Metabolism and Ferroptosis Dual Pathway
Postmenopausal osteoporosis affects hundreds of millions of women worldwide, yet current therapies often carry…
Longevity
GH Receptor Blockade Extends Mouse Lifespan Up to 265 Days
The relationship between growth hormone signaling and aging has long intrigued longevity researchers, but translatable…
Studies
NHS Inpatient Diabetes Care Gaps Persist Despite Five Years of Reform
Inpatient diabetes management is one of the most consequential yet chronically under-resourced areas of hospital…
Longevity
Stopping Statins After 75 Shows No Mortality Increase in Phase 3 Trial
For the millions of older adults who take statins not because they've had a heart attack but simply as a preventive…
Studies
Ketamine and Psychedelics Share Immune-Brain Signaling Pathway Driving Rapid Antidepressant Effects
For the millions living with treatment-resistant depression, the speed of relief matters as much as its depth…
Studies
Global Measles Cases Surpass Pre-Pandemic Levels, Elimination Status Threatened
Measles was once considered a near-conquered disease in high-income nations — a relic of pre-vaccine medicine. That…
Fitness
Fitness Level Explains Neighborhood Deprivation's Toll on Arterial Stiffness in Women
The cardiovascular health gap between women living in economically disadvantaged versus affluent neighborhoods has…
Studies
Global TB Burden Mapped Across 204 Countries: MDR-TB Progress Assessed
Tuberculosis remains one of the most consequential infectious disease challenges of our era — and a major new…
Studies
CSF Proteomics Identifies 23 Dysregulated Proteins in Genetic Frontotemporal Degeneration
Frontotemporal lobar degeneration remains one of the cruelest diagnostic blind spots in neurology — a group of…
Studies
NFL Players Face Nearly Fourfold Neurodegenerative Death Risk Despite Longevity Advantage
The paradox at the heart of professional football's health debate has rarely been captured so starkly: elite athletes…
PREPRINTNutrition
850mg EPA+DHA Daily in Youth Migraineurs: 77% Retention, 100% Biomarker Capture
A quasi-randomized, double-blind, placebo-controlled feasibility trial enrolled 57 children and adolescents (ages…
PREPRINTNutrition
Daily Walnuts Cut Gut Dysbiosis Markers 17.6% in Clinical Trial
A clinical trial measuring 11 fecal metabolites found that regulated walnut intake was associated with a 2.8% increase…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.