Wellbeing
AI Tools in Youth Psychiatry Remain Mostly Unready for Clinical Use
The intersection of a worsening pediatric mental health crisis and a severe child psychiatry workforce shortage has…
Nutrition
Plant-Based UPFs Linked to Similar BMI/Waist Gain Risk as Animal UPFs in 17,000-Person UK Biobank Study
The marketing of plant-based eating as inherently protective against weight gain may need a significant qualifier…
PREPRINTStudies
Medicare Claims Study Flags 5 Atorvastatin Signals in 70,000 Post-Infarction Patients
Analyzing Medicare fee-for-service claims (2017–2019) from 70,130 statin-naive patients aged 65+ hospitalized for…
PREPRINTNutrition
Indian Adults With Diabetes Show Lower Carb Intake But No Improvement in Carb Quality
Among 1,104 Indian adults drawn from 29 healthcare centres across 14 states, carbohydrates supplied 62.1% of total…
PREPRINTWellbeing
Higher Intrinsic Motivation Associated with Better Postpartum LE8 Cardiovascular Health Scores
Among 311 postpartum women in the PETALS-2 prospective cohort, each one-unit increase in intrinsic motivation (IM)…
PREPRINTLongevity
300,927-Patient TAVR Study: 2.7% Need Reintervention at 10 Years, Surgical Explant Survivors Live Longer
Among 300,927 adults undergoing transcatheter aortic valve replacement (TAVR) between 2010 and 2026, cumulative…
PREPRINTLongevity
19 Genomic Loci Linked to Primary Aldosteronism and BP-Independent Cardiovascular Risk Associations
A large trans-ancestry genome-wide association study meta-analysis of primary aldosteronism (PA) uncovered 19…
Longevity
Senolytics Target Cellular Senescence to Reverse Knee Osteoarthritis Pathology
Knee osteoarthritis affects hundreds of millions of adults worldwide, yet every approved treatment addresses symptoms…
Studies
Tirzepatide Beats Semaglutide by 2.87 kg Over 3 Months in Chinese Obesity Cohort
In a 183-person retrospective cohort of Chinese adults with obesity but without diabetes, three months of once-weekly…
Longevity
Semaglutide Reduces hsCRP by 37.8% at 104 Weeks in SELECT Trial, With Early Onset Independent of Weight Loss
Among 17,604 non-diabetic patients with established atherosclerotic cardiovascular disease and overweight or obesity…
Studies
Meta-Analysis: GLP-1 Agonists Linked to 27% Drop in IBD Inflammation Marker and 7.5% Weight Loss in 7,831 Patients
Across 10 studies pooling 7,831 patients with inflammatory bowel disease, GLP-1 receptor agonists produced a mean…
Longevity
Rising NT-proBNP Over Three Years Predicts 7.4% Higher CVD Risk in Elderly
For older adults and their clinicians, a single cardiac biomarker snapshot may be far less informative than watching…
Studies
Diabetes-Multimorbidity Overlap Emerges as Critical Challenge for Aging Adults
When a single chronic disease rarely arrives alone, clinical management becomes exponentially more complex — and for…
Studies
Two Randomized Trials Converge: Debulking Metastatic Colorectal Cancer Offers No Survival Benefit
For decades, surgeons have operated on the intuitive premise that removing visible metastatic tumor burden — debulking…
Longevity
Industrial Lead Exposure Reframed as a Structural Driver of Heart Disease
For decades, coronary heart disease has been framed almost entirely as a consequence of individual choices — diet…
Studies
2026 Dyslipidemia Guidelines Shift Statin Eligibility for Millions in Primary Prevention
Cholesterol management guidelines rarely make headlines outside cardiology circles, yet their ripple effects touch…
Longevity
Epigenetic Clocks Fail to Beat Basic Risk Factors in 9-Year Disease Study
The booming market for biological age testing rests on a compelling premise: that DNA methylation clocks reveal hidden…
Studies
New PREVENT-ASCVD Formula Reclassifies Millions of Cardiovascular Risk Scores
How a clinician calculates cardiovascular risk determines who gets treated — and who doesn't. A shift in the…
Studies
Most High-Risk Americans Still Exceed New 2026 LDL Cholesterol Targets
Cholesterol management remains one of the most modifiable levers in cardiovascular disease prevention, yet a…
Studies
ACC/AHA 2026 Dyslipidemia Guidelines Reshape Cardiovascular Lipid Management Standards
Cardiovascular disease remains the leading cause of death globally, and lipid management sits at the center of…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.