UBE3A Protein Drives Pancreatic Cancer via TERT-Mediated Senescence Resistance
Pancreatic cancer cells exploit the UBE3A protein to resist cellular senescence by degrading mH2A1 histone variants at…
Pancreatic cancer cells exploit the UBE3A protein to resist cellular senescence by degrading mH2A1 histone variants at…
Senescent cells accumulate throughout tissues as we age, releasing inflammatory factors through their senescence-associ…
Laromestrocel, an allogeneic mesenchymal stem cell therapy, produced clinically meaningful improvements in physical fun…
Early detection of vision problems during the critical developmental window could prevent lifelong visual impairments t…
Understanding reproductive timing in seasonal breeders could illuminate evolutionary pressures that shape fertility win…
Nigeria's restrictive legal environment creates a complex intersection of public health challenges and social stigma th…
Pancreatic beta cell dysfunction underlies both type 1 and type 2 diabetes, making any discovery that enhances these in…
Metabolic dysfunction-associated steatotic liver disease affects nearly one billion people globally, yet therapeutic op…
Patients with genetic predisposition to extreme cholesterol levels may finally have access to more effective treatment…
Early detection of Alzheimer's pathology could transform intervention strategies, but current blood-based tests often m…
Blood-based diagnostics could revolutionize Alzheimer's detection by eliminating the need for expensive brain imaging o…
Progressive sensory nerve damage in the cornea may represent an underappreciated pathway of age-related eye dysfunction…
The path from pancreatic injury to cancer may be more predictable than previously understood, potentially opening new w…
Bronchiectasis affects millions globally yet has remained one of respiratory medicine's most inconsistently managed con…
Digital health literacy emerges as a critical vulnerability among aging populations, potentially undermining evidence-b…
The ability to navigate health information online becomes increasingly critical as digital platforms replace traditiona…
Scientists at A*STAR have developed a light-controlled hydrogel system that can adjust tissue stiffness in real-time, r…
A comprehensive analysis of 23,325 UK Biobank participants revealed that adding protein biomarkers to standard clinical…
Analysis of over 30,000 participants across two large cohorts reveals that following current dietary guidelines for fru…
Analysis of 3,432 patients across 57,227 primary care visits revealed that 72% maintained adequate statin adherence (≥8…
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