Wellbeing
Composite Social Disadvantage Index Predicts Midlife Brain Aging Trajectories
The assumption that Alzheimer's risk is primarily a late-life biological problem is increasingly untenable. Evidence…
Studies
Dual GLP-1/Glucagon Receptor Agonist Survodutide Achieves Landmark Weight Loss in Phase 3
The obesity pharmacotherapy landscape is shifting again. While GLP-1 receptor agonists like semaglutide redefined what…
Studies
52-Gene Ciliary Disorder Drives Push for Scalable Human Preclinical Models
For the millions living with chronic respiratory disease rooted in defective cilia, the treatment landscape has long…
Studies
Herbal Compound Lvguidingan Blocks Epilepsy-Linked Sodium Channel Mutations
Sodium channel dysfunction sits at the heart of some of the most treatment-resistant childhood epilepsies, and finding…
Studies
Phase II RIO Trial: Broadly Neutralizing Antibodies Delay HIV Viral Rebound
For people living with HIV, the prospect of a functional cure — one that keeps the virus suppressed without daily…
Studies
Autonomous On-Premise Clinical AI Achieves High Diagnostic Accuracy With Selective Autonomy
The promise of AI in clinical medicine has long collided with a stubborn reality: most large language model-based…
Longevity
P2RX7 Receptor Blockade Clears Senescent Macrophages, Restoring Kidney Function in Aging
Cellular senescence in immune cells is increasingly recognized as a driver of organ decline, not merely a byproduct of…
Studies
Injectable HIV Regimen CAB/RPV-LA Curbs T-Cell Aging Markers Over 72 Weeks
For the estimated 38 million people living with HIV worldwide, viral suppression via antiretroviral therapy is no…
Longevity
Aging Brains Lose DAXX Protein, Triggering Microglial Senescence via Retroviral Activation
The immune cells that patrol the aging brain may be turning against it — not because of external pathogens, but…
Studies
Mucosal TB Vaccine Platform Shows Promise But Fails In Vivo Protection Test
Tuberculosis continues to kill over a million people annually despite decades of BCG vaccination, largely because BCG…
Studies
IgA Nephropathy Progresses to Kidney Failure in 75% Within 25 Years
A disease long dismissed as manageable is now revealing a far more serious trajectory — and the therapeutic landscape…
Longevity
U.S. Stroke-Dementia Deaths Rose 43% Among Elderly Over 25 Years
When nearly one million deaths cluster around two of the most feared conditions in aging — stroke and dementia — the…
Studies
Meta-Analysis Pinpoints Striatum and Insula as Loss Aversion's Neural Core
Understanding why humans fear losses more than they value equivalent gains has profound implications for financial…
Wellbeing
Developmental Review Links Screen Time to Sleep, Attention, and Addiction Risk
As screens become the dominant environment of childhood, the medical community is under pressure to move beyond…
Studies
AI Pathology Framework Cuts Slide Analysis Time by 99% Across 43 Cancer Tasks
Computational pathology is approaching a clinical inflection point, and the bottleneck is no longer algorithmic…
Studies
Whole-Genome Study Links IVF Procedures to De Novo Mutations Affecting Birth Outcomes
For the millions of families who have used assisted reproductive technology, a fundamental question has lingered: do…
Studies
Cannabis Linked to Periodontal Disease and Dry Mouth Across Vulnerable Groups
Oral health is rarely the first concern raised in cannabis policy discussions, yet mounting evidence suggests the…
Studies
AI Outperforms PD-L1 and Clinical Scores in Lung Cancer Immunotherapy Selection
Selecting the right immunotherapy for non-small cell lung cancer patients has long been an educated guess dressed in…
Studies
FMN1 Gene Mutation Disrupts Cochlear Microtubule Architecture, Causing Inherited Hearing Loss
Hereditary hearing loss affects tens of millions globally, yet a significant fraction of cases still lack a genetic…
Studies
Chile's Universal Nirsevimab Program Saved 25,000+ ICU Days in One Season
Respiratory syncytial virus kills more infants globally than any pathogen except malaria, yet until recently no…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.