PREPRINTFitness
High Leisure-Time Physical Activity Slows BMI Gain by 37% Through Age 60
Analysis of 14,993 adults tracked over 34 years reveals that those with the highest leisure-time physical activity gain…
PREPRINTWellbeing
Financial Stress Associated With 18% Higher Heart Disease Risk Among Older Adults
A longitudinal analysis of 7,219 US adults aged 50 and older found that subjective financial strain increased incident…
PREPRINTWellbeing
HPV Vaccination Drops 32% in Urban Malawian Districts, Missing WHO Targets
Analysis of HPV vaccination data across 28 Malawian districts from 2019-2024 reveals concerning coverage gaps, with fir…
PREPRINTLongevity
Live Shingles Vaccine Associated With 36% Lower All-Cause Death Beyond Infection Protection
Analysis of 314,618 adults aged 70+ in England reveals that live shingles vaccination (Zostavax) reduced all-cause mort…
PREPRINTWellbeing
Alpha-Blockers Associated with 48% Higher Heart Failure Risk vs 5α-Reductase Inhibitors
Analysis of nearly 100,000 men with benign prostatic hyperplasia found alpha-blockers increased cardiovascular events c…
PREPRINTNutrition
Pro-Inflammatory Diets Linked to 21% Higher Atrial Fibrillation Risk in 24-Year Study
Adults consuming the most pro-inflammatory diets showed a 21% higher risk of developing atrial fibrillation compared to…
PREPRINTWellbeing
CD93 Receptor Disrupts Lung Capillary Cell Differentiation in Pulmonary Hypertension
Scientists identified a cellular mechanism behind pulmonary hypertension involving defective differentiation of special…
PREPRINTStudies
EHR Algorithms Detect 5.09% Statin Intolerance Rate in Primary Prevention
Six electronic health record algorithms detected statin intolerance in 5.09% of patients prescribed statins for primary…
Studies
TMEM175 Protein Repairs Heart Damage Through Cellular Recycling Pathway
TMEM175, a lysosomal membrane protein, demonstrates protective effects against heart failure following myocardial infar…
Studies
4-IPP Compound Alleviates Diet-Induced Obesity in Mice Through White Fat Browning
Blocking the MIF tautomerase enzyme with compound 4-IPP reversed high-fat diet obesity in mice by reactivating the CD13…
Longevity
Multi-Omics Clock OMICmAge Outperforms DNA Methylation Alone in Aging Assessment
Chen and colleagues developed OMICmAge, which layers multiple molecular signatures onto DNA methylation patterns to cre…
Wellbeing
Fentanyl Users Switch from Injection to Smoking Due to Market Changes
San Francisco researchers documented a notable shift among opioid users transitioning from injecting heroin to smoking…
Studies
Pakistan Study Reveals Telehealth Cuts Patient Costs 58% While Maintaining Quality
Data from 532 Pakistani telehealth users demonstrates dramatic cost reduction from PKR 4,800 for in-person visits to PK…
Studies
PI4P Lipid and GNE-6468 Chemical Cooperatively Trigger STING Immune Activation
Cryo-electron microscopy revealed how phosphatidylinositol 4-phosphate (PI4P) and the experimental compound GNE-6468 wo…
Wellbeing
Injectable Nanoparticles Enable Precise Ultrasound Brain Stimulation for Weeks
Researchers developed hollow silica nanostructures (HSN) that can be injected into specific brain regions to amplify ul…
Studies
Machine Learning Models Predict Spinal Cord Disease 30 Months Early
Machine learning algorithms can identify patients at risk for cervical spondylotic myelopathy—the most common cause of…
Nutrition
Mediterranean Diet Reduces Psoriasis Severity by 32% in Controlled Trial
A 16-week Mediterranean diet intervention reduced psoriasis severity by 32% compared to standard low-fat dietary advice…
Studies
SARS-CoV-2 Nucleocapsid Antibodies Cross-React With Human Proteins
Laboratory analysis reveals that antibodies targeting SARS-CoV-2's nucleocapsid (N) protein exhibit cross-reactivity wi…
Studies
HPV16 Drives 33% of Palestinian Cervical Cancers, Regional Clustering Revealed
Analysis of cervical cancer tissues from 40 Palestinian women revealed HPV infection in 82.5% of cases, with high-risk…
Studies
3D Liver Mapping Reveals Hidden Cirrhosis Damage Patterns
Advanced tissue clearing and computational imaging has produced the first comprehensive 3D reconstructions of human liv…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.