Studies
Codon Optimization in mRNA Therapeutics Creates Unintended Off-Frame Protein Risk
A design assumption underlying virtually every mRNA vaccine and nucleic acid therapeutic may carry an underappreciated…
Studies
NEJM Editorial Examines Mucolytics Role in Acute Respiratory Failure Management
Mucus clearance has long been an underappreciated battleground in critical care, yet the pharmacological tools…
Studies
Azithromycin Shows No Benefit for Young Children with Acute Wheezing
Antibiotic stewardship in pediatric emergency care has long been complicated by the temptation to treat wheezing…
Studies
AI Reads 2D Echo to Detect Heart Obstruction Without Doppler
For the roughly 1-in-500 adults with hypertrophic cardiomyopathy, whether the heart's outflow tract is dangerously…
Wellbeing
Parental Death Linked to Roughly Double Mental Disorder Prevalence in Australian Children vs. Peers Without Loss
When a child loses a parent, the ripple effects extend far beyond grief — they reshape neurodevelopmental trajectories…
Studies
mRNA Cancer Vaccines Show Promising Recurrence Reduction Signals in Early Trials, Mainly Melanoma
For decades, the cancer vaccine field carried a reputation for overpromising and underdelivering — Sipuleucel-T's 2010…
Studies
Biologic Tissue Grafts Tested as Cardiac Assist Strategy in Heart Failure
Heart failure remains one of the leading causes of death globally, and the mechanical devices currently used to…
Studies
Phase III Trial Confirms Hydroxyurea Efficacy for African Children with Sickle Cell Disease
Sickle cell anemia affects millions of children across sub-Saharan Africa, yet evidence-based treatment access has…
Longevity
Metformin's AMPK-mTOR Axis May Redefine Clinical Approaches to Biological Aging
A diabetes drug taken by hundreds of millions of people worldwide may be quietly doing something far more profound…
Studies
Corticosteroid Knee Injections Offer Short Relief But Risk Cartilage Damage Long-Term
For the millions of adults managing knee osteoarthritis, intra-articular corticosteroid injections have become a go-to…
Studies
Oral Ivermectin Plus Permethrin Cream Shows Efficacy Against Severe Scabies
Scabies infestations that progress beyond mild skin irritation into severe, crusted, or treatment-resistant forms…
Longevity
Cancer-Like Mutations in Brain Immune Cells May Fuel Alzheimer's Neuroinflammation
The boundary between cancer biology and neurodegeneration research is proving far more porous than previously assumed…
Studies
NEJM Reviews Myeloproliferative Neoplasm Biology, Diagnosis, and Emerging Therapies
Blood cancers driven by clonal stem cell mutations occupy a unique space in oncology — they evolve slowly, often over…
Studies
Endometriosis Linked to Elevated Psychiatric Burden Up to a Decade Before Formal Diagnosis
For the millions of women living with endometriosis, the condition's invisible toll extends far beyond pelvic pain…
Studies
Serum Protein Panel Tracks Duchenne Muscular Dystrophy Progression Across Multi-Year Trial
For a disease that robs boys of mobility before adolescence, having a reliable blood-based readout of disease…
Studies
AI Matches Human Accuracy in Pain Score Extraction From Clinical Notes
Accurate extraction of patient-reported outcomes from clinical records is a bottleneck that quietly shapes the quality…
PREPRINTStudies
Atorvastatin Linked to 2.2x Hemorrhagic Stroke Risk in Post-Infarction Medicare Patients
Among 70,130 Medicare beneficiaries aged 65+ hospitalized for myocardial or cerebral infarction, initiating…
PREPRINTStudies
871-Person Asian Cohort Finds Gut Microbiome Poorly Predicts Obesity
Shotgun metagenomic analysis of 871 ethnically diverse Singaporean adults (Chinese, Malay, and Indian participants)…
PREPRINTStudies
Ebola Data Showed 8-Fold CFR Uncertainty: Why Outbreak Analytics Need Estimand-First Design
Using longitudinal surveillance records from the 2018–2020 eastern DRC Ebola outbreak and archived forecasts from…
PREPRINTStudies
4 Drug Classes Associated with Shifts in 7 CRC-Linked Gut Bacteria in 1,034-Person Cohort
Among 83 prescription drugs tested in 1,034 colonoscopy-referred adults aged 55–77, 38 altered gut microbial diversity…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.