Studies
MHC-I Loss Shows Opposite Effects on Liver vs Colon Tumors
The immune system's response to cancer cells missing a key identification marker varies dramatically by tumor type…
Studies
A*STAR Develops Microgel-Integrated Microneedle Patches for Improved Protein Loading, Stability, and Transdermal Delivery in Preclinical Tests
The promise of painless, self-administered medicine delivery has moved significantly closer to reality with…
PREPRINTLongevity
Immune Cell Sex Differences Don't Explain Male Mortality Gap
Analysis of 8,822 older adults revealed substantial sex differences in 39 of 48 immune cell biomarkers, with…
PREPRINTStudies
AI Analysis Identifies 19 Age-Specific OSA Comorbidity Patterns in 36,426 Patients
Advanced topic modeling of electronic health records from 36,426 obstructive sleep apnea patients revealed 19 distinct…
PREPRINTLongevity
METS-IR Score Predicts 49% Higher Arrhythmia Risk Over 22 Years
The METS-IR metabolic index demonstrates strong predictive power for cardiac arrhythmias in a comprehensive 22-year…
PREPRINTWellbeing
Maternal Psychiatric Disorders Associated with 19% Higher Offspring Heart Disease Risk
A massive Swedish registry analysis of 4.17 million births found that maternal psychiatric disorders diagnosed before…
PREPRINTLongevity
AI Analysis Links Metolazone, Varenicline to Protective Associations Against Dementia in Million-Veteran Study
Analysis of over one million Veterans' health records using advanced artificial intelligence identified metolazone (a…
Wellbeing
Reflective Rumination Enhances Mood Benefits from Positive Social Media Experiences Among Hispanic Adults
How we mentally process social media interactions may determine whether platforms harm or help our psychological…
Studies
Lipoprotein(a) Elevates Heart Disease Risk Even With Zero Calcium Score
Heart disease prevention may need fundamental recalibration as emerging evidence challenges the reliability of…
Longevity
Progranulin Protein Deficiency Accelerates Vascular Aging Through Cellular Senescence Pathways
Progranulin deficiency in mice triggers premature vascular senescence, causing endothelial dysfunction, enhanced…
Wellbeing
Sex Chromosomes Influence Brain Stress Responses in Mice, Often Independent of Gonad Type
Understanding why women experience depression at twice the rate of men could reshape how we approach mental health…
Studies
EBV Can Cause Lymphomas in Human Cell Mouse Model Without Essential Viral Protein EBNA2
The discovery that Epstein-Barr virus can drive cancer formation without a protein long considered essential…
Studies
AI Maps Complex Protein Mutation Patterns for Enhanced Engineering
Protein engineering has long been hampered by the astronomical complexity of predicting how multiple mutations…
Studies
Healthcare Workers Show Critical Knowledge Gaps During Major Ebola Outbreak
Frontline healthcare preparedness for infectious disease outbreaks remains a critical vulnerability that could…
Studies
Study Proposes HHIP's Role in Epithelial Wound Healing as Potential Mechanism of COPD Susceptibility
Understanding why some smokers develop devastating lung disease while others don't has long puzzled researchers. A…
Studies
Hv1 Proton Channel Structure Reveals Negative-Hydrated Constriction Zone in Active State
The discovery of a previously hidden structural feature in voltage-gated proton channels opens potential therapeutic…
Wellbeing
Neural Backup Systems Enable Robust Predator Escape in Worms
Understanding how nervous systems maintain critical functions despite genetic mutations or cellular damage offers…
Longevity
Cellular Repair Mechanism Uses Fresh Tubulin to Fix Damaged Microtubules
The discovery of how cells repair their internal scaffolding could unlock new approaches to treating neurodegenerative…
Studies
Maternal and Child Health Progress Slowed After 2015 Compared to MDG Era, Global Panel Study Finds
The transition from Millennium Development Goals to Sustainable Development Goals appears to have disrupted momentum…
Wellbeing
Neural Representations of Abstract Phonology Derived from Visual Speech Linked to Reading Ability in Deaf and Hearing Adults
The assumption that reading success requires hearing spoken language may be fundamentally incorrect, with profound…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.