PREPRINTLongevity
Multi-omics reveals 19 biomarkers linking familial longevity to 13-year disease delay
Multi-omics analysis of 495 participants from long-lived families identified 19 specific biomarkers—10 metabolites and…
PREPRINTStudies
ADL Dependence Linked to 5-Fold Higher Odds of Burn Mortality in Geriatric Patients
Analyzing 326 geriatric burn patients, researchers found that dependence in activities of daily living (ADLs)…
Studies
Observational Study: Semaglutide Associated with 0.64-Point Drop in Liver Fibrosis Scores (FIB-4) Among HIV Patients with Advanced Disease
Semaglutide demonstrated significant anti-fibrotic effects in people with HIV, reducing liver fibrosis scores by 0.64…
Studies
Case Reports Suggest Tesamorelin May Offer Targeted Visceral Fat Reduction in HIV Patients Where GLP-1 Agonists Fall Short
Two HIV patients with excess visceral abdominal fat responded differently to targeted therapies, revealing critical…
Longevity
Gut Microbiome Metabolites TMAO, SCFAs Linked to Alzheimer's Pathology and Blood-Brain Barrier Changes
Specific microbial metabolites—short-chain fatty acids, bile acids, and trimethylamine-N-oxide—directly influence…
Studies
Cochrane Review Finds Limited Evidence for Obesity Drugs in Youth
The treatment landscape for childhood obesity may be entering a new phase, but a comprehensive systematic review…
Wellbeing
Letter in PNAS Argues Acupuncture Has No Place in Science-Based Medicine Despite Clinical Use
The medical establishment faces renewed scrutiny over integrative therapies as a prominent scientific journal…
Studies
D614G Mutation Accelerates SARS-CoV-2 Spike Protein Opening Mechanics
Understanding how viral mutations alter protein mechanics could inform future pandemic preparedness strategies and…
Studies
PIKfyve Enzyme Inhibition Blocks Viral Entry Through Membrane Fusion Disruption
Understanding how viruses hijack cellular machinery could unlock new therapeutic targets for pandemic preparedness…
Studies
Liver Insulin Function Predicts Long-Term Prediabetes Reversal Success
The path from prediabetes back to normal glucose metabolism appears far more challenging than previously recognized…
Wellbeing
Skin Tone Bias in Medical Tests Creates Downstream Treatment Disparities
Medical decision-making faces a critical blind spot that could be undermining health equity across diverse…
Supplements
Expert Panel Issues 52 Guidelines for Optimizing GLP-1 Weight Loss Therapy
The explosive adoption of GLP-1 medications like semaglutide and tirzepatide for weight management has created an…
Studies
ASC Protein Controls Critical Inflammatory Switch in Immune Response
A precise molecular brake on inflammation could explain why some people develop chronic inflammatory diseases while…
Studies
Oral Antiviral Cuts COVID Risk by 67% in Household Contacts (Phase 3 Trial)
Living with someone who has COVID-19 creates a uniquely high transmission risk, particularly for families unable to…
Studies
Brain Growth and Upright Walking Drove Human Right-Hand Dominance Evolution
The mystery of why humans overwhelmingly favor their right hand—a trait virtually absent in our primate relatives—now…
Studies
Experimental Antibody NG101 Slows Spinal Cord Degeneration After Injury
Breakthrough findings in spinal cord injury treatment could transform how clinicians approach neural repair in the…
Studies
Female-Biased Gene Networks Predict MYH9 as Regulator of Sex-Specific Fibrous Plaque Formation in Women
Understanding why women under 50 develop different types of heart disease could transform cardiovascular prevention…
Studies
Blood Cell Mutations in Solid Tumors Predict 13% Increased Risk of Death
Cancer patients may face an additional survival threat beyond their primary tumor—rogue blood cells carrying genetic…
Wellbeing
Nature Exposure Shows Equigenic Effects Reducing Mental Health Disparities in Children
Mental health disparities between advantaged and disadvantaged children represent one of modern society's most…
Fitness
Resistance Training Plus HIIT Reverses Multiple Age-Related Decline Markers
Age-related muscle loss and metabolic dysfunction represent inevitable biological processes that significantly impact…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.