PREPRINTLongevity
Blood Cell Mutations Amplify Heart Disease Risk 63% in CKM Patients
Among 307,025 UK Biobank participants, carriers of clonal hematopoiesis of indeterminate potential (CHIP) mutations…
PREPRINTSupplements
Resveratrol 150mg Daily Reduces Inflammation, Cartilage Breakdown in Obese Women
Resveratrol supplementation at 150mg daily provided specific anti-inflammatory and cartilage-protective benefits…
PREPRINTNutrition
8-Electrode BIA Device Shows 97% Correlation With DEXA Scans
An 8-electrode bioelectrical impedance analysis device demonstrated strong correlation with DEXA scans across body fat…
PREPRINTStudies
Atrial Fibrillation Associated with Lower Survival in South African Heart Failure Patients (59% vs 73%)
A prospective study of 136 heart failure patients in Johannesburg found that atrial fibrillation occurs in 21% of…
Wellbeing
Systemic Sclerosis Disrupts Entire Digestive Tract Through Muscle Atrophy
The digestive consequences of systemic sclerosis extend far beyond occasional heartburn, creating a cascade of…
Supplements
Tirzepatide Achieves ~20% Average Weight Loss in Obesity Clinical Trials
The obesity treatment landscape has fundamentally shifted from lifestyle-first approaches to pharmaceutical…
Studies
Cerebellar AMPA Receptor Architecture Reveals Calcium-Permeable GluA1/GluA4 Complex
Brain motor learning and memory formation may depend on a previously uncharacterized protein complex that controls how…
Studies
BiP Chaperone Complex Assembly Determines Proinsulin Folding Success in Diabetes
The intricate machinery that transforms proinsulin into functional insulin may hold critical keys to preventing type 2…
Studies
GLP-1 Drugs Show Mixed Bone Health Effects in Orthopedic Surgery Review
The explosive growth of GLP-1 receptor agonists like semaglutide and tirzepatide creates new considerations for the…
Studies
Brain Cancer Stem Cells Use Serine Production to Resist Radiation
Glioblastoma's notorious resistance to treatment may finally have a biochemical explanation that opens new therapeutic…
Studies
New Menopause Drug Shows Low Persistence Rates in Real-World Analysis
The transition from clinical trials to everyday medical practice often reveals significant gaps in treatment…
Studies
Medicare Insulin Cap Cuts Costs 21% But Doesn't Improve Treatment Adherence
Medicare's insulin affordability crisis may be more complex than simple cost barriers suggest. While the $35 monthly…
Longevity
Nano-microcarriers boost mesenchymal stem cell survival for osteoarthritis cartilage repair
Nano- and microcarrier technology significantly improves mesenchymal stem cell (MSC) viability and targeted delivery…
Studies
Dulaglutide Shows Superior Cardiovascular Protection in Primary Prevention Populations
Dulaglutide emerges as the only GLP-1 receptor agonist demonstrating statistically significant reduction in major…
Fitness
Romanian Deadlifts Generate 60% Higher Hamstring Forces Than Sprint Running
The pursuit of hamstring injury prevention has long centered on matching training loads to the demands athletes face…
Wellbeing
NEJM Editorial Advocates Patient-Centered Approach in Emerging Psychedelic Medicine
The integration of psychedelic compounds into mainstream medicine faces a critical design question that could…
Studies
Down Syndrome Reveals Critical Alzheimer's Mechanisms Through Chromosome 21
The intersection between Down syndrome and Alzheimer's disease offers unprecedented insights into neurodegeneration…
Studies
Long-Read Genome Sequencing Shows Modest Diagnostic Gain Over Standard Testing in Rare Disease Patients
Millions of patients with rare genetic conditions remain undiagnosed despite advances in conventional DNA sequencing…
Longevity
DJ-1 Protein Links Parkinson's Neurodegeneration with Accelerated Skin Aging
The conventional view treats Parkinson's disease as an isolated brain disorder, but emerging evidence reveals a…
PREPRINTStudies
Cardiovascular Polygenic Risk Scores Show ±18 Percentile Point Individual Variability
Analysis of 16 cardiovascular polygenic risk scores in 4,137 participants revealed that while these genetic tests…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.