Nutrition
Gut Bacterium Dysosmobacter Converts Myo-Inositol Into Butyrate, Reversing Liver Steatosis
For the millions of adults with metabolic dysfunction-associated steatotic liver disease — a condition with few…
Longevity
Three Disease Clusters Dominate Multimorbidity in 4.4 Million Older Australians
For clinicians and policymakers treating aging populations, the assumption that chronic disease is scattered and…
Studies
Pan-Pathogen Vaccines Aim to Provide Cross-Protective Immunity Before Next Outbreak
The conventional model of developing one vaccine per pathogen may be the single greatest structural vulnerability in…
Studies
Oral Paltusotine Sustains Acromegaly Control Over Four Years of Treatment
For the roughly 60,000 Americans living with acromegaly, the prospect of replacing lifelong monthly injections with a…
Studies
GRK2 Inhibitors Emerge as Multi-Target Approach for Heart Failure and Beyond
For anyone tracking the frontier of cardiovascular and metabolic drug development, G protein-coupled receptor kinase 2…
Studies
Targeted Protein Degradation Technologies Move Closer to Clinical Reality
For decades, roughly 80% of the human proteome was considered undruggable — proteins that conventional small molecules…
Studies
Gene-Edited Pig Liver Xenografts Reveal Immune and Metabolic Signatures in Human Cross-Circulation
For the millions of patients worldwide who develop acute liver failure each year, the gap between organ demand and…
Nutrition
Biological Age Acceleration Links Inflammatory Diets to Heart-Kidney-Metabolic Syndrome Mortality
For adults managing or trying to prevent the deadly convergence of heart disease, kidney dysfunction, and metabolic…
Studies
Phase 3 Trial: High-Dose IV Vitamin C Fails Severe Burn Patients
For years, high-dose intravenous vitamin C has been positioned as a promising adjunct therapy in critical care…
Studies
Bispecific HIV Antibody 10E8.4/iMab Clears Phase 1 Safety Bar Across Dose Levels
For the roughly 39 million people living with HIV globally, the prospect of a long-acting antibody that could…
Longevity
Four Stem Cell Types Show Distinct Anti-Aging Mechanisms Across Human Tissues
For adults tracking the frontier of longevity medicine, understanding how the body's own regenerative machinery breaks…
Supplements
Citrus Flavonoid Naringin Restores Memory and Hippocampal Plasticity After Chronic Stress
For adults navigating chronic stress — an increasingly universal condition — the prospect of a dietary compound that…
Studies
Review Maps CRISPR, Gene Silencing, and Other Gene-Based Therapies for Inherited Cardiomyopathies
For the roughly one in 500 adults carrying a pathogenic variant linked to inherited cardiomyopathy, current management…
Studies
AI-Accelerated MRI Halves Scan Time Without Sacrificing MS Lesion Detection
For the roughly 2.9 million people living with multiple sclerosis worldwide, routine MRI surveillance is a clinical…
Wellbeing
Targeted Support Package Mitigates Rise in Burnout Among Pregnant Medical Residents in Randomized Trial
Physician burnout is a well-documented crisis, but one subgroup — pregnant and postpartum residents and fellows — has…
PREPRINTLongevity
AI Reads Heart Ultrasounds to Detect Hidden Kidney Disease in 850M-Patient Crisis
A deep learning model trained on 325,377 echocardiography videos from 62,818 patients at Cedars-Sinai can detect…
PREPRINTStudies
BiLID Index Predicts Cardiac Muscle Damage Better Than Application Count in PFA Ablation
A retrospective analysis of 1,556 pulsed-field ablation (PFA) applications in 23 patients undergoing pulmonary vein…
PREPRINTStudies
4.2% of Children Show Persistent High BP, Yet Only 1.2% Diagnosed
Among 71,683 children aged 6–17 tracked across three or more primary care visits from 2017–2024, 4.2% (2,911)…
PREPRINTLongevity
AI Segments Heart Fat Depot in 60 Seconds vs. 58-Minute Manual Process
A deep-learning pipeline using nnU-Net architecture trained on 165 cardiac MRI cases achieved automated segmentation…
PREPRINTStudies
HeartBioPortal 3.0 Integrates 594M Allele Observations Into Single Cardiovascular Genomics Hub
HeartBioPortal 3.0 (HBP 3.0) consolidates cardiovascular genomic intelligence into a single browser-based environment…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.