PREPRINTStudies
Socioeconomic Factors Linked to Up to 81% Lower Odds of GLP-1 RA Use in CKM Patients: NHANES Analysis
Among 4,520 NHANES participants (representing ~84 million U.S. adults with Type 2 diabetes and Stage 2…
PREPRINTLongevity
DNMT3A Clonal Hematopoiesis Associated with Heightened Trained Immunity Responses in Obese Adults
In a small but mechanistically rich human cohort, individuals with DNMT3A-driven clonal hematopoiesis (CH) — 17…
PREPRINTLongevity
60% of 'Normal' Blood Volume Heart Failure Patients Harbor Hidden Anemia
In a retrospective analysis of 395 Class II–III chronic heart failure patients, only 30% of those labeled as having…
Nutrition
Rome V Criteria and Gut-Brain Axis Reshape IBS Clinical Management Framework
Irritable bowel syndrome affects roughly one in ten adults globally, yet its management remains inconsistent and often…
Wellbeing
Cyberbullying Victimization Linked to Teen Conduct Problems Through Impulse-Control Difficulties
Understanding precisely how online harassment translates into lasting psychological harm matters enormously for…
Studies
Macrophage Protease MMP14 Drives Obesity-Linked Inflammation and Insulin Resistance
Understanding why obesity so reliably triggers systemic metabolic dysfunction—insulin resistance, fatty liver…
Nutrition
Oxalate Transporters Downregulated in IBD Cohorts and Colitis Models, Suggesting Potential Role in Gut Inflammation
For the millions living with Crohn's disease or ulcerative colitis, diet remains a frustratingly murky variable…
Studies
Cannabis, Cocaine, and Amphetamines Linked to Higher Stroke Risk, with Causal Evidence for Cannabis
Stroke prevention has long focused on classical vascular risk factors — hypertension, atrial fibrillation, diabetes…
Longevity
Aged Muscle Niche Sabotages Stem Cell Therapies—PSC Reprogramming Offers Escape Route
Sarcopenia's regenerative failure stems from a dual collapse: resident satellite cells (SCs) become exhausted and…
Longevity
Exercise Modulates Brain p21 Senescence Signals Via Dose-Dependent Three-State Model
The cyclin-dependent kinase inhibitor p21 (CDKN1A) behaves in fundamentally opposing ways across exercise contexts in…
Studies
Crash Notification Technology Saves Lives But Remains Largely Undeployed
Every minute between a serious vehicle crash and first medical contact shapes survival odds — a reality that makes the…
PREPRINTNutrition
Food Support Linked to 68% Lower TB Mortality and Much Higher Medication Adherence in Benin-Togo Natural Experiment
A prospective cohort study across 13 sites in Benin and Togo (n=769) exploited a natural policy experiment: Benin…
PREPRINTNutrition
Low-Dose 27mg Iron Linked to Better Gut Diversity and Lower IL-6 in Small RCT of Female Soccer Players
A 3-month randomized controlled trial in 23 female soccer players (median age 21) found that 27 mg/day elemental iron…
PREPRINTNutrition
AI Meta-Analysis Links Lutein, Beta-Carotene to Lower Risk Across 3 Female Cancers
An automated evidence-synthesis platform called MetaFemina, integrating large language model (LLM)-assisted extraction…
PREPRINTLongevity
Single AI Model Estimates Right Ventricular Function and Flags Pulmonary Hypertension from One Echo View
A unified deep-learning model called PH-ECHO-AI, trained on 8,416 echocardiographic clips from four public datasets…
PREPRINTLongevity
10+ Medications Associated with Nearly Doubled Mortality Risk in 4,110 Colombian Seniors Over 79 Months (Preprint)
Among 4,110 community-dwelling Colombian adults aged 60+ followed for a mean of 79 months, polypharmacy (5–9…
Studies
Menin-MEK Inhibitor Combo Shows Synergy Against High-Risk Pediatric AML Subtype
For children diagnosed with certain aggressive leukemias, existing therapies often fall devastatingly short. A…
Studies
Low-Frequency Motor Thalamus DBS Shows Promise for Improving Speech and Swallowing After Brain Injury
For millions of adults living with chronic speech and swallowing disabilities after brain injury, effective treatment…
Wellbeing
Multilingual Alzheimer's Patients Show Distinct Default Mode Network Connectivity Patterns
For decades, the idea that speaking multiple languages could buffer the brain against dementia has attracted both…
Supplements
Dietary Yeast Beta-Glucan Reprograms Bone Marrow to Restore Tumor Immunity in Obesity
Obesity doesn't just add weight — it fundamentally rewires the immune system in ways that linger even after weight…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.