Wellbeing
Severe Sleep Apnea Disrupts Brain's Nightly Restoration Mechanism, Study Finds
The brain's ability to reset itself overnight may be quietly eroding in millions of people with untreated sleep apnea…
Studies
Expert Consensus Defines GAE Protocol for Refractory Chronic Knee Pain
For the millions of adults living with chronic knee pain unresponsive to physical therapy, injections, or…
Studies
LRRC8A Protein Loss in Arterial Muscle Cells Triggers Blood Pressure-Lowering Cascade
Hypertension remains one of the most modifiable risk factors for cardiovascular disease and stroke, yet the molecular…
Studies
Four-Drug HER2-Targeted Regimen Shows Clinical Promise in Biliary Tract Cancer
Biliary tract cancers — encompassing cholangiocarcinoma and gallbladder cancer — remain among the most lethal…
Longevity
Menopause Proteomics Reveal Hormone-Driven Molecular Signatures Tied to Later Dementia Risk
For decades, the connection between menopause and accelerated cognitive decline has been clinically observed but…
Studies
AI Tool Detects Esophageal Cancer on Standard CT Scans With High Accuracy
Esophageal cancer ranks among the deadliest malignancies precisely because it is rarely caught early — most patients…
Studies
PATHFINDER 2 and NHS-Galleri Data Reveal MCED Test Gaps Before Population Rollout
Early cancer detection has long been the holy grail of oncology, but translating a promising blood test into a…
Longevity
Prime-Edited Mutator Pigs Confirm mtDNA Errors Accelerate Mammalian Aging
Understanding why mitochondria deteriorate with age—and whether that deterioration drives aging or merely accompanies…
Wellbeing
Group Medical Visits Deliver Four Distinct Social Support Types for Chronic Pain
Chronic pain affects roughly one in five adults, yet conventional primary care visits rarely address the profound…
Studies
Ten Genetic Loci Linked to Infant Temperament, Predicting Adult Personality Traits
Long before personality is shaped by experience, biology is already laying groundwork. A large-scale genomic…
Wellbeing
Acupuncture, Yoga, and Mindfulness Show Clinical Value in Radiation Oncology
As survival rates for blood cancers climb, the medical community faces a growing challenge: managing the cumulative…
PREPRINTFitness
400 MET·min/day Caps Central Adiposity Protection in 5,273 High-Risk Older Adults
Among 5,273 PREDIMED participants aged 60–80 (61% women) at high cardiovascular risk, those accumulating ≥100…
PREPRINTNutrition
NRS-2002 Score ≥3 Triples In-Hospital Mortality Risk Across 178,607 Admissions
Across 178,607 hospitalizations at the University of Leipzig Medical Center (2017–2023), patients scoring ≥3 on the…
PREPRINTLongevity
4-Factor Patient Profile Predicts Blood Pressure Control Better Than Any Single Predictor
Reanalysis of the VALUE trial — a double-blind outcomes study of 15,313 hypertensive adults — finds that combining…
PREPRINTLongevity
GLP-1 Drugs Cut Stroke Risk 17%, But Blood Pressure Explains Only 4%
Across 7 randomized controlled trials enrolling 50,617 adults with type 2 diabetes at high cardiovascular risk, GLP-1…
PREPRINTLongevity
AI-ECG Achieves 0.92 AUROC for HCM Detection, 60-Fold Risk Stratification with Polygenic Score
An AI model applied to standard 12-lead ECG images demonstrated exceptional performance in identifying hypertrophic…
Studies
GLP-1 Drug Discontinuation Triggers Weight Regain and Cardiovascular Risk Cycles
Stopping a GLP-1 receptor agonist or tirzepatide isn't a neutral event — emerging evidence suggests it may set off a…
Longevity
Poor Diet Drives CVD Risk 21–41% Via Accelerated Biological Aging
Across 52,718 UK Biobank participants followed for 12 years, accelerated biological aging — measured via Phenotypic…
Longevity
Senolytics Convert Docetaxel's Pro-Metastatic SASP Into Anti-Tumor Immunity
Docetaxel and other DNA-damaging chemotherapies reliably induce cellular senescence in prostate cancer cells, but the…
Studies
Global TB Deaths Fell 37% Since 1990, But MDR-TB Threatens Progress
Tuberculosis remains one of the most consequential and underappreciated infectious threats in global health — and new…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.