Studies
Low-Dose Rivaroxaban Shows No Cardiovascular Benefit in Advanced CKD Trial
Patients with advanced chronic kidney disease face cardiovascular mortality rates that dwarf those of the general…
Studies
ELABELA Peptide Reverses Hypertrophic Cardiomyopathy in Dual Mouse Models
Hypertrophic cardiomyopathy is the most common inherited heart disease and a leading cause of sudden cardiac death in…
Studies
Low-Dose Rivaroxaban Shows Mixed Cardiovascular Results in Advanced CKD Trial
Anticoagulation in patients with severely impaired kidney function has long been a clinical tightrope — the very…
Longevity
Premature Menopause Associated with 12% Higher Hypertension Risk Over 14 Years in UK Biobank Study
Cardiovascular disease remains the leading cause of death among women, yet female-specific risk factors are…
Studies
Low-Dose Rivaroxaban Tested for Cardiovascular Protection in Advanced Kidney Disease
Cardiovascular mortality in advanced chronic kidney disease represents one of medicine's most persistent and…
Studies
Histidine Emerges as Dual Biomarker for Cancer Risk and Treatment Response
Amino acid metabolism sits at the intersection of nutrition and oncology in ways that could reshape how clinicians…
Studies
Primary Aldosteronism Screened in Under 2% of Eligible Hypertensive Patients
A silent hormone disorder may be driving cardiovascular and kidney damage in millions of hypertensive adults who are…
Wellbeing
Emergency Departments May Inadvertently Worsen Loneliness in Vulnerable Patients
For millions of socially isolated adults, the emergency department may function less as a medical venue and more as an…
Studies
DeepSeek's Medical Footprint: First Systematic Map of 371 Studies
Open-source large language models are quietly reshaping how clinicians, educators, and researchers interact with…
PREPRINTLongevity
Blood Ratio HRR Predicts 3-Year Heart Events After Stent Placement
Among 626 Vietnamese patients followed prospectively for three years after percutaneous coronary intervention (PCI)…
PREPRINTStudies
ACHD-AP Physiology Score Predicts 14% Mortality in Highest-Risk Surgical Patients
Among 295 adults undergoing congenital heart surgery at a single academic center (2018–2022, median age 30), the ACHD…
PREPRINTLongevity
Out-of-Hospital Falls Linked to Fourfold Higher Cardiac Event Risk in Robust Coronary Patients
In a retrospective cohort of 2,139 coronary heart disease (CHD) patients followed for a median 36 months…
PREPRINTLongevity
GLP-1 Drugs Linked to 11% Lower All-Cause Inpatient Use in 4,677-Patient Medicare Study of Heart Failure and Obesity
Among 4,677 matched pairs of Medicare Advantage beneficiaries (mean age 72) with concurrent heart failure and obesity…
PREPRINTLongevity
Metformin Slows Frailty Accumulation and Cuts Biological Age by 0.4 Years Annually
In a 145-person, two-year randomized double-blind placebo-controlled trial, metformin produced a steady improvement in…
Longevity
GLP-1 Agonists Show Antitumor, Fertility, and Addiction Benefits Beyond Metabolic Use
Emerging preclinical and observational evidence positions semaglutide and tirzepatide — GLP-1 and dual GIP/GLP-1…
Studies
GLP-1 Agonists May Suppress Female Sexual Desire Via Dopamine Pathway Dampening
Despite delivering substantial weight loss and metabolic improvement, GLP-1 receptor agonists (semaglutide…
Supplements
Semaglutide Linked to MASLD Improvement in HIV Patients in Small Pilot Study
Twenty-four weeks of low-dose semaglutide produced significant reductions in metabolic dysfunction-associated…
Supplements
High-Dose Tirzepatide 15mg Linked to Anhedonia-Like Symptoms in 3-Case Series
Three female patients on high-dose tirzepatide (15 mg/week) for obesity developed anhedonia-like symptoms — emotional…
Studies
Gut Microbiome Feedback to 778 African Women Costs $29–59, Linked to Self-Reported Behavior Changes
A nested mixed-methods study within the AWI-Gen Wave 2 cohort delivered personalized gut microbiome reports to 778…
Longevity
Senolytic and Senomorphic Approaches to Chondrocyte Senescence in Knee OA: Preclinical Promise and Early Clinical Trials
Cellular senescence — where chondrocytes enter irreversible cell-cycle arrest while resisting apoptosis, ferroptosis…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.