Studies
Synthetic THC Cuts PTSD Nightmare Frequency and Intensity in Controlled Trial
For the millions of adults living with post-traumatic stress disorder, nightmares are not merely unpleasant — they…
Studies
Cannabis for PTSD: Only Nabilone Shows Controlled-Trial Benefit in 3,598 Patients
Despite a surge in cannabis prescriptions for trauma survivors, the controlled evidence base remains far thinner than…
Wellbeing
Home Death Achieved by Combining Cardiac Device Withdrawal With Aid-in-Dying
End-of-life care for patients dependent on implanted life-sustaining technology presents one of modern medicine's most…
Studies
Controlled Trial Finds Low Abuse Potential and No Clinically Meaningful Withdrawal with Oral Kratom in Healthy Adults
As kratom use surges across the United States — driven by its reputation for pain relief, mood enhancement, and energy…
Fitness
Three Childhood Lifestyle Factors Associated with Altered Gait Biomechanics in Elementary School Children
How children walk is shaped long before adulthood, and the habits formed during elementary school years may set…
PREPRINTStudies
Autonomic Instability—Not Cardiac Fibrosis—Predicts AF 20 Minutes Before Onset
In a prospective single-center study of 6,697 adults undergoing elective cardiac surgery (2023–2025), preoperative…
PREPRINTLongevity
Mendelian Randomization Links 7 Biomarkers—Including Triglycerides and SHBG—to Vascular Calcification
Using two-sample bidirectional Mendelian randomization across 363,228 individuals for biomarker GWAS data and 28,654…
PREPRINTStudies
LASr + LGE-CMR Combo Hits 91% AUC for AF Detection in Mitral Regurgitation
In 46 patients with moderate-to-severe degenerative mitral regurgitation (DMR), integrating left atrial reservoir…
PREPRINTLongevity
Stress Leaves 841 DNA Methylation Marks That Predict Heart Disease 17 Years Later
An epigenome-wide association study of 3,857 postmenopausal women in the Women's Health Initiative identified 841…
Wellbeing
Pregnancy Complications Linked to Higher Depression, Anxiety, and PTSD Risk
Mental health conditions now rank among the leading drivers of maternal death in the United States, yet the women at…
Longevity
Semaglutide Requires AgRP Neurons—Not Suppression—for Female Weight Loss in Mice (Preprint)
Contrary to the longstanding assumption that GLP-1 receptor agonists like semaglutide work by suppressing hypothalamic…
Studies
Senescent Glioma Cells Deploy SASP to Hijack Tumor Microenvironment, Fuel Recurrence
Cellular senescence in glioblastoma (WHO Grade IV) is not the tumor-suppressive endpoint it represents in normal…
Wellbeing
Strong Family Bonds and School Recognition Linked to Lower Teen Suicide Risk in Study of Over 190,000 Pennsylvania Students
Teen suicide prevention has long concentrated on reducing individual risk factors — depression, substance use…
Studies
ER Injuries Linked to 34–98% Higher Mental Health Diagnosis Risk Within One Year
Most conversations about injury care focus on physical recovery — broken bones, wound healing, rehabilitation. But the…
Fitness
Visual Biofeedback During ACL Training Reshapes Brain Activity in Teen Athletes
Anterior cruciate ligament tears disproportionately strike adolescent female athletes, and a substantial portion of…
Studies
Chimeric Protein Strategy Restores SOX17 Tumor Suppressor in Bile Duct Cancer Cells
Cholangiocarcinoma — bile duct cancer — carries one of the bleakest prognoses in oncology, with five-year survival…
Supplements
Ginkgo Biloba's Cardiovascular Mechanisms Mapped in Comprehensive Pharmacological Review
For adults seeking evidence-based approaches to cardiovascular protection, understanding exactly how botanical…
Studies
FOSL1-KCa3.1 Axis Links Mitochondrial Hyperfusion to Cartilage-Destroying Ferroptosis
Osteoarthritis affects hundreds of millions of adults globally, yet disease-modifying treatments remain elusive. Most…
Studies
9-mg Mazdutide Achieves Significant Weight Reduction in Chinese Obesity Trial
The global obesity epidemic rarely receives tailored pharmacological solutions for specific populations, yet metabolic…
Studies
Oral GLP-1 Agonist Plus Insulin Cuts HbA1c Beyond Insulin Alone
For the roughly one-third of people with type 2 diabetes who remain poorly controlled despite daily insulin…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.