Studies
Contrast-Free MRI Protocol Equals Standard Scanning for Prostate Cancer
The PRIME clinical trial establishes that biparametric MRI (bpMRI) achieves equivalent diagnostic performance to multip…
Studies
Predictive Models Personalize Platelet Transfusion Decisions for Preterm Babies
Advanced computational models now calculate individualized bleeding and mortality risks for preterm infants receiving p…
Supplements
JAMA Trial Shows Myo-Inositol Ineffective for PCOS Pregnancy Outcomes
A double-blind, placebo-controlled trial examining myo-inositol supplementation in pregnant women with polycystic ovary…
Studies
Five Cancer Types Drive 70% of Under-50 Deaths Despite Prevention Advances
Breast, colorectal, lung, brain, and lymphoid cancers account for approximately 70% of cancer deaths in Americans under…
Studies
JAMA Challenges Simple Calorie Model of Obesity Causation
JAMA presents evidence contradicting the conventional calories-in-calories-out explanation for weight gain, highlightin…
Wellbeing
Stress-Related Activity Partly Mediates Association Between Depression/Anxiety and Cardiovascular Events
Analysis of cardiovascular event data reveals chronic stress serves as a primary biological mediator connecting depress…
Studies
Fixed-Dose Combination Pills May Improve Hypertension Control Over Monotherapy
Fixed-dose combination medications demonstrate measurably better blood pressure control compared to single-agent therap…
Nutrition
Food Preservatives Linked to 49% Higher Type 2 Diabetes Risk in Nearly 109,000-Person French Cohort
Nitrate and nitrite preservatives, ubiquitous in processed meats and packaged foods, demonstrate a dose-dependent relat…
Studies
Elevated Lp(a) Biomarker Predicts Three-Decade Cardiovascular Risk in Women
Lipoprotein(a) emerges as a powerful long-term cardiovascular predictor in women, with elevated concentrations associat…
Studies
Hospital Deaths from Alcohol Rise Despite Stable Admission Rates
Between 2016 and 2022, while the frequency of alcohol-related hospital admissions plateaued in the United States, patie…
Studies
Systematic Review Finds Weak Evidence for Pediatric Melatonin Efficacy
A comprehensive systematic review examining melatonin's therapeutic value in neurotypical children reveals substantial…
Studies
Physician Training Plus Patient Education Halves Unnecessary Antibiotic Prescriptions
A cluster randomized trial across rural Chinese clinics demonstrated that combining physician training with real-time d…
Studies
Pragmatic Intervention Reduces Antibiotic Resistance in Chinese Healthcare Settings
A large-scale implementation trial in China demonstrates that antibiotic stewardship programs can effectively reduce an…
Longevity
Blocking Fat Tissue Growth Hormone Receptors Preserves Brain Function in Aging
Eliminating growth hormone receptors specifically in fat tissue dramatically protected aged mice from brain deteriorati…
Studies
CD8 T Cells Deploy Caspase-8 Death Pathway Against Brain Parasites
Caspase-8 deficiency in CD8+ T cells dramatically impairs the immune system's ability to control Toxoplasma gondii brai…
Studies
Split-Course Radiation Matches Standard Treatment in Frail Cancer Patients
A randomized trial of 190 frail elderly patients with head and neck cancer found that hypofractionated split-course rad…
Fitness
Exercise Reduces Cancer Fatigue in Advanced Lung Cancer Patients
Pooled analysis of eight randomized trials involving 749 advanced lung cancer patients demonstrates that structured exe…
Studies
N4BP2 Enzyme Drives Cancer-Causing DNA Chaos Through Chromosome Fragmentation
A cytoplasmic enzyme called N4BP2 has been identified as a key driver of catastrophic chromosome shattering in cancer c…
PREPRINTLongevity
Left Atrial Failure Point Identified at 107mL Preload Volume
Cardiac computed tomography analysis of 975 patients revealed that the left atrium's booster pump function follows an i…
PREPRINTWellbeing
Clinician Subjective Cognitive Assessments Outperform Patient Self-Reports in 4,290 Adults
Analysis of 4,290 older adults across cognitive health spectrums reveals that clinician and informant reports of subjec…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.