Studies
Wildfire Smoke Associated with 18% Higher NYC Elementary School Absences
As wildfire seasons grow longer and smoke plumes increasingly blanket distant cities, the health burden extends well…
Studies
Triple-Reporter Mouse Model Tracks Tumors Across Whole-Body to Cellular Scale
Understanding how cancers evolve, spread, and respond to treatment has long been constrained by the limitations of…
Studies
Large Prenatal Acetaminophen Study Links Use to Lower Large-for-Gestational-Age Risk
For millions of pregnant individuals who reach for acetaminophen to manage pain or fever, the question of fetal safety…
Studies
Tau Deposits Impair Cognition in PSP Via Remote Cortical Network Connections
For decades, the assumption in neurodegenerative disease research has been that brain damage causes dysfunction where…
Nutrition
Invasive E. coli Pathobionts Promote Colorectal Cancer Stemness via Hippo Pathway in Apc(Min/+) Model
The assumption that colorectal cancer is primarily a genetic disease is being steadily dismantled by microbiome…
Longevity
Engineered Enzyme Reverses Irreversible Glycation Damage in Aged Human Tissue
For decades, a core assumption in aging biology held that certain molecular scars accumulate irreversibly — that once…
Studies
Bayesian EHR Model Uncovers 21 Replicable Disease Signatures Across 683,000 Patients
Most disease risk models treat conditions as isolated events — a myocardial infarction here, a diabetes diagnosis…
Studies
Computational Framework Reveals How Analysis Choices Shape Synaptic Plasticity Interpretations
How the brain encodes memories at the cellular level depends critically on the physical shape of dendritic spines…
Wellbeing
RBFOX1 Splicing Gene Acts as Central Hub Linking Depression, Anxiety, and Neuroticism
Understanding why major depression so frequently travels alongside anxiety, irritability, and neurotic personality…
Supplements
Natural Compounds Reveal Dual Molecular Targets for Obesity and Fatty Liver Disease
As the global burden of metabolic disease accelerates, the pharmaceutical pipeline for fatty liver disease remains…
Nutrition
Gut Microbiome Shields Glial Cells From Tau and Amyloid Accumulation in Fly Model
The gut-brain axis may be more central to Alzheimer's disease progression than previously recognized. If microbial…
Studies
GLP-1 Drugs Linked to Rare Optic Nerve Injury Amid Mixed Retinal Data
As semaglutide and its GLP-1 receptor agonist relatives become among the most widely prescribed drugs on the planet…
Studies
Tau Deposits Linked to Remote Cortical Network Disruption and Cognitive Decline in PSP
For anyone tracking neurodegeneration research, the assumption has long been that brain damage causes symptoms where…
Studies
New 'Cough Control' Threshold Defined Beyond Minimal Improvement Benchmarks
For the millions of adults living with refractory chronic cough — a condition that can persist for years and severely…
Longevity
Sarcopenia Requires Multi-Target Fix: No Single Mechanism Explains MPS Decline
A mechanistic, multiscale kinetic model of leucine-mediated signaling and protein metabolism in human skeletal muscle…
Longevity
Hypothesis: Exercise May Suppress CTSS Protease via AMPK-TFEB Pathway to Reduce Alzheimer's Pathology
A novel theoretical framework proposes that exercise confers Alzheimer's neuroprotection primarily by suppressing…
Longevity
BPF Plastic Chemical Converted to Cardiotoxic NAP Metabolite via Gut Microbiota Sat1 Pathway in Mouse Models
Bisphenol F (BPF) — detected in 90.5% of 285 human urine samples at a median of 1.16 ng/μg creatinine — drives cardiac…
Studies
Cyclospora Parasite Poses Elevated Risk in Transplant Recipients, Study Finds
For the millions of adults living with suppressed immune systems — whether from organ transplants, cancer treatment…
Studies
Mitochondrial Dysfunction Genes Linked to Immune Shifts in Early Epilepsy
Epilepsy affects roughly 50 million people globally, yet why some brains tip into chronic seizure cycles after an…
Studies
Nuclear α-Ketoglutarate Pathway Links Mitochondrial Enzymes to Brain Gene Regulation
The idea that mitochondrial metabolism directly shapes which genes are active in the brain — and by extension…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.