Studies
Network Meta-Analysis Ranks Seven Recreational Therapies for Dementia Cognition
For the millions of caregivers and clinicians managing mild cognitive impairment and dementia, choosing among music…
PREPRINTLongevity
Childhood Poverty Outpredicts Unemployment in County-Level Heart Disease Deaths
Across 1,982 U.S. counties, pediatric poverty emerged as the single strongest county-level predictor of cardiovascular…
PREPRINTLongevity
Neighborhood Disadvantage Triples HFpEF Readmission Risk at 90–365 Days Post-Discharge
Among 6,702 adults hospitalized for heart failure with preserved ejection fraction (HFpEF) between 2014 and 2022…
PREPRINTLongevity
36% of Czechs Show Pre-Clinical Heart Failure Signs, Mortality Jumps 10-Fold by Stage D
Analyzing a decade of Czech national health registry data (2015–2024) covering the full population, a claims-based…
PREPRINTStudies
AR-Guided FEVAR Cuts Radiation, Cannulation Time vs. Fluoroscopy in Preclinical Ovine/Phantom Studies
An augmented reality navigation platform combining intravascular ultrasound (IVUS), electromagnetic position tracking…
PREPRINTLongevity
pTau-217 Threshold Method—Not Platform—Determines Alzheimer's Blood Test Positivity
In a cohort of 990 participants from the Bio-Hermes-001 study, plasma phosphorylated tau-217 (pTau-217) was measured…
Studies
Lymph Node Scaffold Density Predicts Breast Cancer Survival After Chemotherapy
The structural architecture of immune tissue — not just tumor biology — may hold untapped prognostic power in breast…
Studies
Semaglutide Exposure in Early Pregnancy Linked to Altered Weight Gain Outcomes
As GLP-1 receptor agonists like semaglutide become ubiquitous tools for managing obesity, an urgent clinical gap has…
Studies
B Cell Antibody Responses in Lymph Nodes Drive CTLA-4 Immunotherapy Efficacy Against Glioma
Brain cancer immunotherapy has long been dominated by a T cell-centric narrative — checkpoint inhibitors were assumed…
Studies
AI Colonoscopy Tools Show Mixed Results in Lynch Syndrome Surveillance
For individuals carrying Lynch syndrome mutations, colonoscopy surveillance is a cornerstone of cancer prevention…
Supplements
GLP-1 Agonists and Diet Shrink Heart Fat Beyond Weight Loss Alone
A multilevel meta-regression of 42 interventional studies (50 arms, 1,890 participants) found that BMI reduction…
Studies
Ampyrone Activates Human Tyrosinase, Opening Door for Albinism Treatment
For the roughly 1 in 17,000 people born with oculocutaneous albinism and millions more affected by acquired…
Studies
Vibration Device Plus Video Games Cut Vaccine Fainting Risk 25% in Teens
Fainting and near-fainting after routine vaccinations are among the most disruptive events in adolescent clinical care…
Wellbeing
Live Sports Spectatorship Linked to Heart-Rate Synchrony and Endogenous Oxytocin Dynamics
The persistent failure of intranasal oxytocin trials to reliably improve social functioning has pushed researchers…
Studies
Nirsevimab Cuts Infant RSV Hospitalizations Across Two Consecutive Seasons
Most infant immunization data stops at one season — making it genuinely difficult to judge whether protective effects…
Studies
Enteric Infectious Diseases Cause 1.27 Million Deaths in 2023, Down from 3.69 Million in 1990, but 2025 GAPPD Target Elusive
More than a million deaths annually from gut infections may sound like a historical relic in an era of vaccines and…
PREPRINTLongevity
3,029 Mexican CCS Patients Show 74% Miss LDL Targets Despite 93% Statin Use
Among 3,029 Mexican adults with chronic coronary syndrome (CCS) enrolled across ~50 centers between September 2024 and…
PREPRINTLongevity
Explainable ML Model Achieves AUC 0.84 for Post-Discharge Heart Failure Mortality Prediction in 3,933-Patient Preprint
Among 3,933 heart failure patients discharged from New South Wales hospitals, 45.2% experienced emergency readmission…
PREPRINTLongevity
Drug-Coated Devices Associated With 86% Higher Wound Healing Rate in Observational CLTI Study
Among 341 consecutive patients with chronic limb-threatening ischemia (CLTI) undergoing infrainguinal endovascular…
PREPRINTStudies
Low-Volume TAVR Hospitals Linked to ~10% Higher Adjusted Odds of 1-Year Mortality in 215,000 Medicare Patients
Among 215,335 Medicare patients undergoing transcatheter aortic valve replacement (TAVR) across 788 U.S. hospitals…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.