Studies
Triple Hormone Agonist Retatrutide Drives Substantial Weight Loss in Phase III Trial
Obesity pharmacotherapy is entering a new era, and the latest data suggest the ceiling on drug-induced weight loss may…
PREPRINTWellbeing
Insomnia at 50 Predicts Cognitive Decline; Same Symptom Reverses After 75
Across 16,884 adults from three longitudinal cohorts (ELSA, Whitehall II, and Rush MAP), difficulty falling asleep at…
PREPRINTStudies
CGM-Detected Glucose Spikes Raise Liver Scarring Risk 28–59% in Non-Diabetics
In 1,071 adults from the Framingham Heart Study Third Generation cohort (mean age 60.2, BMI 28.2, 56% normoglycemic)…
PREPRINTWellbeing
Six Lifestyle Clusters Predict Dementia Risk: Worst Combo Raises Hazard 2.4×
Among 151,832 UK Biobank participants aged 60–69, six distinct clusters of co-occurring modifiable risk factors were…
PREPRINTFitness
Daily Air Pollution Spikes Cut Next-Day Steps by 483 in Adults Over 50
In a micro-longitudinal study of 67 UK adults aged 50–85, days with higher-than-usual personal PM2.5 exposure — just…
PREPRINTNutrition
Erythritol and Xylitol Show No Platelet-Activating Effect in Crossover Trial
A randomized, single-blind crossover trial in 14 healthy adults tested whether acute oral doses of erythritol (50 g)…
Studies
SGLT2 Inhibitors Show No Clear Anti-Inflammatory Effect Across 47 Trials
Pooling 47 randomized controlled trials, SGLT2 inhibitor therapy produced no statistically significant reductions in…
Nutrition
CBT-Enhanced Liver Program Cuts Cardiovascular Events 64% in Fatty Liver Disease
A randomized controlled trial of 286 adults with metabolic dysfunction-associated steatotic liver disease (MASLD)…
Studies
Endogenous Oestradiol Levels Don't Predict Heart Risk or Death in Women 70+
In 5,535 women aged 70 or older enrolled in the Sex Hormones in Older Women (SHOW) Study — a sub-study of the ASPREE…
Nutrition
Gut Butyrate Producers Determine Whether Protein Aids Post-Stroke Recovery
In 152 older stroke patients (mean age 78.4 years) undergoing inpatient rehabilitation, the benefit of dietary protein…
Studies
Oral GLP-1 Pill Cuts HbA1c 1.45% in Drug-Naive Type 2 Diabetes
Injectable GLP-1 receptor agonists have transformed metabolic medicine, but needle aversion and cold-chain logistics…
PREPRINTLongevity
Night Shift Work Raises CVD Risk 7% Per 5 Years; Morning Types Hit Hardest
Among 69,458 female nurses followed from 2009 to 2021 in the Nurses' Health Study II, each additional 5 years of…
PREPRINTWellbeing
Marijuana Cuts HRV by 0.47ms and Fragments Sleep Across 17,000 Wearable Users
Across 16,965 wearable-device users contributing over 5.2 million person-days of data, nightly marijuana use was…
PREPRINTWellbeing
Social Isolation Raises Death Risk 34%; Transport Mode Modifies the Harm
In a UK Biobank cohort of 490,114 adults aged 40–69, followed from 2006 to 2022, social isolation was associated with…
PREPRINTWellbeing
Four Sleep Dimensions Tied to Cognitive Function in Adults 55+
In a Chicago-based observational study of 324 adults aged 55 and older (64% women, 37% Black, 14% Hispanic/Latino)…
PREPRINTNutrition
Oat Milk Delivers Far Fewer Amino Acids Than Dairy, Even With Added Pea Protein
In a randomized crossover trial, 12 healthy men consumed 750 ml of semi-skimmed dairy milk, a standard oat-based drink…
Nutrition
KCl Tablets Cut Systolic BP ~8 mmHg by Flushing Hidden Tissue Sodium
In a 40-participant prospective study of adults with essential hypertension or hyperaldosteronism, personalised oral…
Studies
OAGB Cuts Long-Term Weight Regain Risk 66% vs Sleeve Gastrectomy
Across 1,498 adults followed for a median of 53–66 months after bariatric surgery, all three procedures achieved…
Nutrition
High Fat and SFA Intake Linked to 8× Mortality Risk in Cirrhosis
In a 5-year prospective cohort of 121 ambulatory patients with newly diagnosed cirrhosis, higher dietary fat intake…
Studies
GLP-1 + SGLT2i Combo Cuts CKD Mortality 45% vs Monotherapy
In a propensity-matched real-world cohort of 32,448 adults with chronic kidney disease, adding a GLP-1 receptor…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.